peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase
neutrophil degranulation
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
25797
70536
Ensembl
ENSG00000115828
ENSMUSG00000024084
UniProt
Q16769
Q9CYK2
RefSeq (mRNA)
NM_012413
NM_027455 NM_001316729
RefSeq (protein)
NP_036545
NP_001303658 NP_081731
Location (UCSC)
Chr 2: 37.34 – 37.37 Mb
Chr 17: 79.36 – 79.4 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Glutaminyl-peptide cyclotransferase is an enzyme that in humans is encoded by the QPCT gene.[5][6]
This gene encodes human pituitary glutaminyl cyclase, which is responsible for the presence of pyroglutamyl residues in many neuroendocrine peptides. The amino acid sequence of this enzyme is 86% identical to that of bovine glutaminyl cyclase.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000115828 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000024084 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Song I, Chuang CZ, Bateman RC Jr (Jan 1995). "Molecular cloning, sequence analysis and expression of human pituitary glutaminyl cyclase". J Mol Endocrinol. 13 (1): 77–86. doi:10.1677/jme.0.0130077. PMID 7999256.
Glutaminyl-peptide cyclotransferase is an enzyme that in humans is encoded by the QPCT gene. This gene encodes human pituitary glutaminyl cyclase, which is responsible...