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Pydiflumetofen information


Pydiflumetofen
Names
Preferred IUPAC name
3-(Difluoromethyl)-N-methoxy-1-methyl-N-[1-(2,4,6-trichlorophenyl)-2-propanyl]-1H-pyrazole-4-carboxamide
Other names
SYN545974
Identifiers
CAS Number
  • 1228284-64-7 checkY
3D model (JSmol)
  • Interactive image
Beilstein Reference
20345474
ChEBI
  • CHEBI:87576 checkY
ChemSpider
  • 34501423 checkY
ECHA InfoCard 100.252.186 Edit this at Wikidata
EC Number
  • 817-852-1
PubChem CID
  • 56933411
UNII
  • WHG7I49FAK
CompTox Dashboard (EPA)
  • DTXSID60894826 Edit this at Wikidata
InChI
  • InChI=1S/C16H16Cl3F2N3O2/c1-8(4-10-12(18)5-9(17)6-13(10)19)24(26-3)16(25)11-7-23(2)22-14(11)15(20)21/h5-8,15H,4H2,1-3H3 checkY
    Key: DGOAXBPOVUPPEB-UHFFFAOYSA-N checkY
SMILES
  • CC(CC1=C(C=C(C=C1Cl)Cl)Cl)N(C(=O)C2=CN(N=C2C(F)F)C)OC
Properties[1]
Chemical formula
C16H16Cl3F2N3O2
Molar mass 426.67
Appearance Off-white solid
Density g/cm3
Melting point 113°C
Solubility in water
1.5 mg/L (20 °C)
log P 3.8
Hazards
GHS labelling:[2]
Pictograms
GHS08: Health hazard GHS09: Environmental hazard
Signal word
Warning
Hazard statements
H351, H361f, H410
Precautionary statements
P203, P273, P280, P318, P391, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Pydiflumetofen is a broad spectrum fungicide used in agriculture to protect crops from fungal diseases. It was first marketed by Syngenta in 2016 using their brand name Miravis. The compound is an amide which combines a pyrazole acid with a substituted phenethylamine to give an inhibitor of succinate dehydrogenase,[3] an enzyme that inhibits cellular respiration in almost all living organisms.[4]

  1. ^ Pesticide Properties Database. "Pydiflumetofen". University of Hertfordshire.
  2. ^ "GHS Classification". pubchem.ncbi.nlm.nih.gov. 2023-07-22. Retrieved 2023-07-27.
  3. ^ Irie, Makoto (2017). "Pydiflumetofen" (PDF). FAO. Retrieved 2023-07-27.
  4. ^ Bénit, Paule; Kahn, Agathe; Chretien, Dominique; et al. (2019). "Evolutionarily conserved susceptibility of the mitochondrial respiratory chain to SDHI pesticides and its consequence on the impact of SDHIs on human cultured cells". PLOS ONE. 14 (11): e0224132. Bibcode:2019PLoSO..1424132B. doi:10.1371/journal.pone.0224132. PMC 6837341. PMID 31697708.

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