Pruritic papules and scattered nodules can be seen (a) on the legs, (b) on the arms and (c) on the trunk of this patient with prurigo nodularis.
Scattered excoriated nodules across the extensor surface of both hands
Specialty
Dermatology
Prurigo nodularis (PN), also known as nodular prurigo, is a skin disorder characterized by pruritic (itchy), nodular lesions, which commonly appear on the trunk, arms and legs.[1] Patients often present with multiple excoriated nodules caused by chronic scratching. Although the exact cause of PN is unknown, PN is associated with other dermatologic conditions such as untreated or severe atopic dermatitis and systemic causes of pruritus including liver disease and end stage kidney disease.[2] The goal of treatment in PN is to decrease itching. PN is also known as Hyde prurigo nodularis, or Picker's nodules.[3]
Prurigonodularis (PN), also known as nodular prurigo, is a skin disorder characterized by pruritic (itchy), nodular lesions, which commonly appear on...
Prurigo is an itchy eruption of the skin. Specific types include: Prurigonodularis Actinic prurigo Besnier's prurigo (a specific type of atopic dermatitis)...
It is also used for the treatment of eosinophilic esophagitis and prurigonodularis. The most common side effects reported by the US Food and Drug Administration...
of lesions can cause thickening or lichenification of the skin or prurigonodularis (generalized nodules that are severely itchy). AD is typically diagnosed...
trial, showing efficacy and safety of nemolizumab in patients with prurigonodularis. Nemolizumab is a monoclonal antibody that blocks the signaling of...
and oncostatin M. It is developed by Kiniksa Pharmaceuticals for prurigonodularis. "Vixarelimab". go.drugbank.com. Retrieved 19 November 2023. Sofen...
is a single case report of its use in the successful treatment of prurigonodularis, a difficult to treat pruritic eruption of the skin. However it belongs...
Pemphigoid nodularis is a cutaneous condition that is a variant of bullous pemphigoid that has skin lesions mimicking prurigonodularis. The antibody involved...
through behaviour modification and anti-inflammatory medication. Prurigonodularis is a related disorder showing multiple lumps. (ICD-10 L28.0; L28.1)...
factor – a type of antibody. Possible associations include Hyde's prurigonodularis and membranoproliferative glomerulonephritis. Cardiomyopathy with...
Strong pruritus may cause excoriated papules or lesions resembling prurigonodularis to appear. Both adults and children can experience mucous membrane...
diseases showed significant over-expression of METRNL in psoriasis, prurigonodularis, actinic keratosis and atopic dermatitis. METRNL is also up-regulated...
to xerosis, skin lesions like excoriation, crusts, impetigo, and prurigonodularis may also develop as a result of repeated scratching. There are several...
dermatosis, and these features may help differentiate the condition from prurigonodularis. Since koebnerization can aggravate perforating disorders, treatment...
eczema, psoriasis, neurodermatitis, in some varieties of acne and prurigonodularis and especially in varicose ulcers. Barduzzi vigorously advocated in...
is unclear. Some scientists believe that it may be a variation of prurigonodularis. The theory that most scientists agree upon is that Kyrle disease...
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