Platypnea or platypnoea is shortness of breath (dyspnea) that is relieved when lying down, and worsens when sitting or standing upright. It is the opposite of orthopnea.[1] The condition was first described in 1949 and named in 1969.[2]
A related condition, orthodeoxia, describes the clinical finding of low oxygen saturation in the upright position, which improves when lying down.[3]
Platypnea and orthodeoxia (low oxygen levels when in upright posture) can co-exist, and this combination is named platypnea-orthodeoxia syndrome.[4][5] The syndrome is considered extremely rare however.[4]
^Dorland's Illustrated Medical Dictionary (32 ed.). Elsevier Saunders. 2012. p. 1459. ISBN 978-0-8089-2418-0.
^Robin ED, McCauley RF (1997). "An analysis of platypnea-orthodeoxia syndrome including a 'new' therapeutic approach". Chest. 112 (6): 1449–51. doi:10.1378/chest.112.6.1449. PMID 9404736.
^Dorland's Illustrated Medical Dictionary (32 ed.). Elsevier Saunders. 2012. p. 1337. ISBN 978-0-8089-2418-0.
^ abCheng TO (2002). "Mechanisms of platypnea-orthodeoxia: what causes water to flow uphill?". Circulation. 105 (6): e47. doi:10.1161/circ.105.6.e47. hdl:10553/76643. PMID 11839642.
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