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Pierre Chambon information


Pierre Chambon
Born (1931-02-07) 7 February 1931 (age 93)
Mulhouse, France
NationalityFrench
Known fornuclear hormone receptors
AwardsRichard Lounsbery Award (1982)
Harvey Prize (1987)
Sir Hans Krebs Medal (1990)
Louis-Jeantet Prize for Medicine (1991)[1]
Welch Award in Chemistry (1998)
Louisa Gross Horwitz Prize (1999)
Albert Lasker Award for Basic Medical Research (2004)
Alfred P. Sloan, Jr. Prize (2003)
Gairdner Foundation International Award (2010)
Louisa Gross Horwitz Prize (2018)
Scientific career
InstitutionsInstitute for Genetics and Cellular and Molecular Biology [fr]

Pierre Chambon (French pronunciation: [pjɛʁ ʃɑ̃bɔ̃]; born 7 February 1931 in Mulhouse, France) was the founder of the Institute for Genetics and Cellular and Molecular Biology [fr] in Strasbourg, France.[2] He was one of the leading molecular biologists who utilized gene cloning and sequencing technology to first decipher the structure of eukaryotic genes and their modes of regulation. His major contributions to science include the identification of RNA polymerase II (B)[nb 1], the identification of transcriptional control elements, the cloning and dissection of nuclear hormone receptors, revealing their structure and showing how they contribute to human physiology. His group was also one of the first to demonstrate, biochemically and electron-microscopically, that the nucleosome is the smallest unit of chromatin (Cell, Vol. 4, 281–300, 1975). He accomplished much of his work in the 1970s – 1990s.

Chambon was elected a Foreign Associate of the US National Academy of Sciences and to the French Académie des Sciences in 1985, a foreign member of the Royal Swedish Academy of Sciences in 1987.[3] He was awarded the Louisa Gross Horwitz Prize from Columbia University in 1999 and a second time in 2018. In 2003 he was awarded the March of Dimes Prize in Developmental Biology. He received the Albert Lasker Award for Basic Medical Research in 2004 for his work in the field. In 2010, Chambon was awarded the Gairdner Foundation International Award "for the elucidation of fundamental mechanisms of transcription in animal cells and to the discovery of the nuclear receptor superfamily".[4] In 2018 he received the Louisa Gross Horwitz Prize for a second time.[5]

  1. ^ "Professor Pierre CHAMBON | Jeantet". 2017-10-01. Retrieved 2023-08-11.
  2. ^ "Pierre Chambon - USIAS - University of Strasbourg". www.usias.fr (in French). Retrieved 2018-04-30.
  3. ^ "Kungl. Vetenskapsakademien". 2017-11-10. Archived from the original on 2017-11-10. Retrieved 2023-08-11.
  4. ^ Pierre Chambon, M.D. - The Gairdner Foundation Archived June 11, 2010, at the Wayback Machine
  5. ^ "The Louisa Gross Horwitz Prize". Columbia University Irving Medical Center. 2022-11-11. Retrieved 2023-08-11.


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increasing public awareness about this devastating disease. 2004 Basic Pierre Chambon For the discovery of the superfamily of nuclear hormone receptors and...

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Physiology or Medicine) 1998 Arnold J. Levine, Bert Vogelstein 1999 Pierre Chambon, Robert Roeder, Robert Tjian 2000 H. Robert Horvitz (2002 Physiology...

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Mulhouse

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receive the Legion of Honour, the highest decoration granted in France. Pierre Chambon (born 1931), biologist Cléopatre Darleux (born 1989), handball goalkeeper...

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University of Strasbourg

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(*1927) Martin Karplus (*1930), Nobel Prize 2013 Yves Michaud (*1930) Pierre Chambon (*1931) John Warwick Montgomery (*1931) Zemaryalai Tarzi (*1933) Alberto...

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King Faisal Prize

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1988 Science Biology  United Kingdom Ricardo Miledi Professor  France Pierre Chambon Professor 1989 Science Physics  Germany Theodor W. Hänsch  Professor...

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Louis Pasteur University

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Martin Karplus (1930–), professor of chemistry, Nobel Prize in 2013 Pierre Chambon (1931–), professor of biology, Lasker Award in 2004, Canada Gairdner...

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Chromosome conformation capture

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X-inactivation. In 1973/1974, chromatin fiber was discovered. In 1975, Pierre Chambon coined the term nucleosomes. In 1982, Chromosome territories were discovered...

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Inserm

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to take up a post-doctoral fellowship in the laboratory of Professor Pierre Chambon. In 1977, while still in this role, Gannon was appointed Chargé de Recherche...

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