Protein-coding gene in the species Homo sapiens
PSAPL1 Identifiers Aliases PSAPL1 , prosaposin-like 1 (gene/pseudogene), prosaposin like 1 (gene/pseudogene), prosaposin like 1External IDs MGI: 1924193; HomoloGene: 105928; GeneCards: PSAPL1; OMA:PSAPL1 - orthologs Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4p16.1 Start 7,430,285 bp[1] End 7,434,930 bp[1]
Gene location (Mouse) Chr. Chromosome 5 (mouse)[2] Band 5|5 B3 Start 36,361,365 bp[2] End 36,363,912 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of thigh skin of abdomen vulva nipple skin of hip human penis lower lobe of lung body of stomach pharynx right testis
Top expressed in skin of external ear pyloric antrum epithelium of stomach lip skin of back esophagus conjunctival fornix superior surface of tongue condyle mucous cell of stomach
More reference expression data
BioGPS
Gene ontology Molecular function
enzyme activator activity
G protein-coupled receptor binding Cellular component
extracellular region
lysosome
extracellular space
cytoplasm
cytosol Biological process
regulation of lipid metabolic process
prostate gland growth
adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway
epithelial cell differentiation involved in prostate gland development
sphingolipid metabolic process
lipid metabolism
positive regulation of catalytic activity Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 4: 7.43 – 7.43 Mb Chr 5: 36.36 – 36.36 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Proactivator polypeptide-like 1 is a protein in humans that is encoded by the PSAPL1 gene. It is a member of the saposin family of proteins.
[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000178597 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043430 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^
"Entrez Gene: Prosaposin-like 1 (gene/pseudogene)". Retrieved 2013-04-11 .
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