PRDM2 information

PRDM2
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2JV0, 2QPW
Identifiers
Aliases	PRDM2, HUMHOXY1, KMT8, MTB-ZF, RIZ, RIZ1, RIZ2, PR domain 2, PR/SET domain 2, KMT8A
External IDs	OMIM: 601196; MGI: 107628; HomoloGene: 40822; GeneCards: PRDM2; OMA:PRDM2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	13,825,079 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	143,212,995 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; secondary oocyte; ; buccal mucosa cell; ; middle temporal gyrus; ; epithelium of colon; ; Brodmann area 46; ; Brodmann area 10; ; frontal pole; ; bone marrow cells; ; Brodmann area 23;
	Top expressed in
	interventricular septum; ; spermatocyte; ; spermatid; ; granulocyte; ; zygote; ; tail of embryo; ; genital tubercle; ; otic vesicle; ; muscle of thigh; ; visual cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; methyltransferase activity; transferase activity; DNA binding; zinc ion binding; histone-lysine N-methyltransferase activity; metal ion binding; nucleic acid binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; chromatin DNA binding; sequence-specific DNA binding;
Cellular component	nucleus; Golgi apparatus;
Biological process	histone lysine methylation; methylation; regulation of transcription, DNA-templated; determination of adult lifespan; transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	7799
	110593
	ENSG00000116731
	ENSMUSG00000057637
	Q13029
	n/a
NM_001007257; NM_001135610; NM_012231; NM_015866; NM_001393986;
	NM_001393987; NM_001393988
	NM_001081355; NM_001256380
	NP_001007258; NP_001129082; NP_036363; NP_056950
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

PR domain zinc finger protein 2 is a protein that in humans is encoded by the PRDM2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000116731 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000057637 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Buyse IM, Shao G, Huang S (May 1995). "The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein". Proceedings of the National Academy of Sciences of the United States of America. 92 (10): 4467–71. Bibcode:1995PNAS...92.4467B. doi:10.1073/pnas.92.10.4467. PMC 41965. PMID 7538672.
^ "Entrez Gene: PRDM2 PR domain containing 2, with ZNF domain".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000116731 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000057637 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid7538672-5] Buyse IM, Shao G, Huang S (May 1995). "The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein". Proceedings of the National Academy of Sciences of the United States of America. 92 (10): 4467–71. Bibcode:1995PNAS...92.4467B. doi:10.1073/pnas.92.10.4467. PMC 41965. PMID 7538672.

[entrez-6] "Entrez Gene: PRDM2 PR domain containing 2, with ZNF domain".

PRDM2 information

and 8 Related for: PRDM2 information

PRDM2

List of human transcription factors

H3K9me2

Histone methyltransferase

SET domain

Retinoblastoma protein

Estrogen receptor alpha

Jyotsna Dhawan