PNRC2 information

PNRC2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4B6H
Identifiers
Aliases	PNRC2, proline rich nuclear receptor coactivator 2
External IDs	OMIM: 611882 MGI: 106512 HomoloGene: 9821 GeneCards: PNRC2
Gene location (Human)
Chr.	Chromosome 1 (human)
End	23,963,462 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	135,601,161 bp
RNA expression pattern
	Top expressed in
	germinal epithelium; ; parietal pleura; ; trabecular bone; ; visceral pleura; ; lactiferous duct; ; lower lobe of lung; ; mucosa of urinary bladder; ; renal medulla; ; metanephric glomerulus; ; superficial temporal artery;
	Top expressed in
	parotid gland; ; external carotid artery; ; seminal vesicula; ; medial ganglionic eminence; ; internal carotid artery; ; pituitary gland; ; molar; ; atrium; ; Paneth cell; ; cumulus cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	P-body; nucleus; cytoplasm; nucleoplasm; Golgi apparatus; cytosol;
Biological process	regulation of transcription, DNA-templated; deadenylation-independent decapping of nuclear-transcribed mRNA; transcription, DNA-templated; nuclear-transcribed mRNA catabolic process, nonsense-mediated decay;
	Sources:Amigo / QuickGO
Orthologs
	55629
	52830
	ENSG00000189266
	ENSMUSG00000028675
	Q9NPJ4
	Q9CR73
	NM_017761
	NM_026383
	NP_060231
	NP_080659
	Wikidata
View/Edit Human	View/Edit Mouse

Proline-rich nuclear receptor coactivator 2 is a protein that in humans is encoded by the PNRC2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000189266 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028675 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Zhou D, Chen S (Sep 2001). "PNRC2 is a 16 kDa coactivator that interacts with nuclear receptors through an SH3-binding motif". Nucleic Acids Res. 29 (19): 3939–48. doi:10.1093/nar/29.19.3939. PMC 60244. PMID 11574675.
^ "Entrez Gene: PNRC2 proline-rich nuclear receptor coactivator 2".

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