PLXNA3 information

PLXNA3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3IG3
Identifiers
Aliases	PLXNA3, 6.3, HSSEXGENE, PLXN3, PLXN4, XAP-6, plexin A3
External IDs	OMIM: 300022; MGI: 107683; HomoloGene: 7481; GeneCards: PLXNA3; OMA:PLXNA3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	154,477,779 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	73,388,295 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; stromal cell of endometrium; ; right hemisphere of cerebellum; ; ganglionic eminence; ; left ovary; ; right ovary; ; tibial nerve; ; right coronary artery; ; right uterine tube; ; sural nerve;
	Top expressed in
	ventricular zone; ; ganglionic eminence; ; genital tubercle; ; motor neuron; ; female urethra; ; lateral amygdaloid nucleus; ; Anterior olfactory nucleus; ; perirhinal cortex; ; entorhinal cortex; ; medial amygdaloid nucleus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; transmembrane signaling receptor activity; semaphorin receptor activity;
Cellular component	integral component of membrane; membrane; intracellular membrane-bounded organelle; plasma membrane; semaphorin receptor complex; cell junction; nucleus; integral component of plasma membrane;
Biological process	regulation of axon extension involved in axon guidance; negative chemotaxis; negative regulation of axon extension involved in axon guidance; neuron projection extension; multicellular organism development; neuron projection guidance; branchiomotor neuron axon guidance; positive regulation of cytoskeleton organization; pyramidal neuron development; facial nerve structural organization; hippocampus development; trigeminal nerve structural organization; semaphorin-plexin signaling pathway; signal transduction; axon guidance; semaphorin-plexin signaling pathway involved in axon guidance; negative regulation of cell adhesion; regulation of cell shape; regulation of cell migration; regulation of GTPase activity; positive regulation of axonogenesis;
	Sources:Amigo / QuickGO
Orthologs
	55558
	18846
	ENSG00000130827
	ENSMUSG00000031398
	P51805
	P70208
	NM_017514
	NM_008883; NM_001358129
	NP_059984
	NP_032909; NP_001345058
	Wikidata
View/Edit Human	View/Edit Mouse

Plexin-A3 is a protein that in humans is encoded by the PLXNA3 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000130827 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031398 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bione S, Tamanini F, Maestrini E, Tribioli C, Poustka A, Torri G, Rivella S, Toniolo D (Jan 1994). "Transcriptional organization of a 450-kb region of the human X chromosome in Xq28". Proc Natl Acad Sci U S A. 90 (23): 10977–81. doi:10.1073/pnas.90.23.10977. PMC 47904. PMID 8248200.
^ Chen EY, Zollo M, Mazzarella R, Ciccodicola A, Chen CN, Zuo L, Heiner C, Burough F, Repetto M, Schlessinger D, D'Urso M (Jun 1997). "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci". Hum Mol Genet. 5 (5): 659–68. doi:10.1093/hmg/5.5.659. PMID 8733135.
^ "Entrez Gene: PLXNA3 plexin A3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000130827 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031398 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8248200-5] Bione S, Tamanini F, Maestrini E, Tribioli C, Poustka A, Torri G, Rivella S, Toniolo D (Jan 1994). "Transcriptional organization of a 450-kb region of the human X chromosome in Xq28". Proc Natl Acad Sci U S A. 90 (23): 10977–81. doi:10.1073/pnas.90.23.10977. PMC 47904. PMID 8248200.

[pmid8733135-6] Chen EY, Zollo M, Mazzarella R, Ciccodicola A, Chen CN, Zuo L, Heiner C, Burough F, Repetto M, Schlessinger D, D'Urso M (Jun 1997). "Long-range sequence analysis in Xq28: thirteen known and six candidate genes in 219.4 kb of high GC DNA between the RCP/GCP and G6PD loci". Hum Mol Genet. 5 (5): 659–68. doi:10.1093/hmg/5.5.659. PMID 8733135.

[entrez-7] "Entrez Gene: PLXNA3 plexin A3".

PLXNA3 information

and 3 Related for: PLXNA3 information

PLXNA3

Plexin

Sema domain