PGPEP1 information

PGPEP1
Identifiers
Aliases	PGPEP1, PAP-I, PGP, PGP-I, PGPI, Pcp, pyroglutamyl-peptidase I, PGI
External IDs	OMIM: 610694; MGI: 1913772; HomoloGene: 9793; GeneCards: PGPEP1; OMA:PGPEP1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	18,369,950 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	70,660,388 bp
RNA expression pattern
	Top expressed in
	cardia; ; renal medulla; ; tendon of biceps brachii; ; pylorus; ; inferior ganglion of vagus nerve; ; internal globus pallidus; ; external globus pallidus; ; vena cava; ; ventral tegmental area; ; subthalamic nucleus;
	Top expressed in
	right kidney; ; proximal tubule; ; ventricular zone; ; human kidney; ; epithelium of small intestine; ; neural tube; ; adrenal gland; ; yolk sac; ; jejunum; ; ileum;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	peptidase activity; cysteine-type peptidase activity; hydrolase activity; pyroglutamyl-peptidase activity;
Cellular component	cytoplasm; cytosol;
Biological process	proteolysis;
	Sources:Amigo / QuickGO
Orthologs
	54858
	66522
	ENSG00000130517
	ENSMUSG00000056204
	Q9NXJ5
	Q9ESW8
NM_001300927; NM_001308366; NM_017712; NM_001329471; NM_001329476;
	NM_001329477; NM_001329478
	NM_023217
NP_001287856; NP_001295295; NP_001316400; NP_001316405; NP_001316406;
	NP_001316407; NP_060182
	NP_075706
	Wikidata
View/Edit Human	View/Edit Mouse

The PGPEP1 gene in humans encodes the enzyme Pyroglutamyl-peptidase I.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000130517 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000056204 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: PGPEP1 pyroglutamyl-peptidase I".