Protein-coding gene in the species Homo sapiens
PARP16 Available structures PDB Ortholog search: PDBe RCSB
Identifiers Aliases PARP16 , ARTD15, C15orf30, pART15, poly(ADP-ribose) polymerase family member 16External IDs MGI: 2446133; HomoloGene: 9878; GeneCards: PARP16; OMA:PARP16 - orthologs Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q22.31 Start 65,234,460 bp[1] End 65,300,618 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 C Start 65,102,635 bp[2] End 65,146,506 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte gonad testicle Achilles tendon canal of the cervix ganglionic eminence left ovary right ovary granulocyte right lobe of liver
Top expressed in saccule otic vesicle lacrimal gland liver right kidney Ileal epithelium islet of Langerhans granulocyte proximal tubule brown adipose tissue
More reference expression data
BioGPS
Gene ontology Molecular function
transferase activity
kinase binding
protein serine/threonine kinase activator activity
protein binding
glycosyltransferase activity
NAD+ ADP-ribosyltransferase activity
protein ADP-ribosylase activity
Cellular component
integral component of membrane
nuclear envelope
endoplasmic reticulum
endoplasmic reticulum membrane
membrane
endoplasmic reticulum tubular network
cytosol
Biological process
endoplasmic reticulum unfolded protein response
protein auto-ADP-ribosylation
response to unfolded protein
protein ADP-ribosylation
negative regulation of cell death
positive regulation of protein serine/threonine kinase activity
NAD biosynthesis via nicotinamide riboside salvage pathway
cellular response to leukemia inhibitory factor
IRE1-mediated unfolded protein response
protein mono-ADP-ribosylation
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_017851 NM_001316943 NM_001316944
RefSeq (protein) NP_001303872 NP_001303873 NP_060321
Location (UCSC) Chr 15: 65.23 – 65.3 Mb Chr 9: 65.1 – 65.15 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Poly (ADP-ribose) polymerase family, member 16 is a protein in humans that is encoded by the PARP16 gene.
[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000138617 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000032392 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Entrez Gene: Poly (ADP-ribose) polymerase family, member 16". Retrieved 2013-04-03 .