Protein-coding gene in the species Homo sapiens
PAOX Identifiers Aliases PAOX , PAO, polyamine oxidase (exo-N4-amino), polyamine oxidaseExternal IDs OMIM: 615853; MGI: 1916983; HomoloGene: 72096; GeneCards: PAOX; OMA:PAOX - orthologs Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10q26.3 Start 133,379,261 bp[1] End 133,391,694 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F4 Start 139,695,712 bp[2] End 139,717,137 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm right lobe of liver spleen sural nerve monocyte parotid gland Brodmann area 9 prefrontal cortex internal globus pallidus amygdala
Top expressed in liver duodenum lip white adipose tissue esophagus zone of skin bone marrow urinary bladder secondary oocyte stomach
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
polyamine oxidase activity
N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity
spermine:oxygen oxidoreductase (spermidine-forming) activity
N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity
oxidoreductase activity
signaling receptor binding Cellular component
cytoplasm
peroxisome
peroxisomal matrix
cytosol Biological process
spermine metabolic process
spermine catabolic process
spermidine catabolic process
positive regulation of spermidine biosynthetic process
polyamine biosynthetic process
putrescine biosynthetic process
polyamine catabolic process
putrescine catabolic process
protein targeting to peroxisome Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_152911 NM_207129
RefSeq (protein) NP_690875
Location (UCSC) Chr 10: 133.38 – 133.39 Mb Chr 7: 139.7 – 139.72 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase is an enzyme that in humans is encoded by the PAOX gene.[5] [6]
^ a b c GRCh38: Ensembl release 89: ENSG00000148832 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025464 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ Cite error: The named reference pmid12660232 was invoked but never defined (see the help page). ^ Cite error: The named reference entrez was invoked but never defined (see the help page). 
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