Nodavirus endopeptidase (EC 3.4.23.44, Black Beetle virus endopeptidase, Flock House virus endopeptidase) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
Hydrolysis of an asparaginyl bond involved in the maturation of the structural protein of the virus, typically -Asn-Ala- or -Asn-Phe-
The enzyme is coded by several nodaviruses that are insect pathogens.
^Zlotnick A, Reddy VS, Dasgupta R, Schneemann A, Ray WJ, Rueckert RR, Johnson JE (May 1994). "Capsid assembly in a family of animal viruses primes an autoproteolytic maturation that depends on a single aspartic acid residue". The Journal of Biological Chemistry. 269 (18): 13680–4. PMID 8175803.
^Johnson JE, Schneemann A (1998). "Nodavirus endopeptidase". In Barrett AJ, Rawlings ND, Woessner JF (eds.). Handbook of Proteolytic Enzymes. London: Handbook of Proteolytic Enzymes. pp. 964–967.
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Nodavirusendopeptidase (EC 3.4.23.44, Black Beetle virus endopeptidase, Flock House virus endopeptidase) is an enzyme. This enzyme catalyses the following...
N5). Family N1: The known autolytic cleavage is mediated by the nodavirusendopeptidase, from the C-terminus of the coat protein and only occurs within...