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Nitidine information


Nitidine
Chemical structure of nitidine
Names
Preferred IUPAC name
2,3-Dimethoxy-12-methyl-9H-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium
Identifiers
CAS Number
  • 6872-57-7 checkY
3D model (JSmol)
  • Interactive image
ChemSpider
  • 4345
PubChem CID
  • 4501
UNII
  • 933301178Z checkY
CompTox Dashboard (EPA)
  • DTXSID60218846 Edit this at Wikidata
InChI
  • InChI=1S/C21H18NO4/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22/h4-10H,11H2,1-3H3/q+1
    Key: KKMPSGJPCCJYRV-UHFFFAOYSA-N
  • InChI=1/C21H18NO4/c1-22-10-13-7-17(23-2)18(24-3)8-15(13)14-5-4-12-6-19-20(26-11-25-19)9-16(12)21(14)22/h4-10H,11H2,1-3H3/q+1
    Key: KKMPSGJPCCJYRV-UHFFFAOYAL
SMILES
  • C[N+]1=CC2=CC(=C(C=C2C3=C1C4=CC5=C(C=C4C=C3)OCO5)OC)OC
Properties
Chemical formula
C21H18NO4+
Molar mass 348.37 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Nitidine is a benzophenanthridine alkaloid found in species of the genus Zanthoxylum , notably in Zanthoxylum nitidum. This compound has an anti-malarial activity.[1]

  1. ^ Bouquet, J., et al. (2012). Biological activities of nitidine, a potential anti-malarial lead compound. Malaria Journal 11:67

and 16 Related for: Nitidine information

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Nitidine

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Nitidine is a benzophenanthridine alkaloid found in species of the genus Zanthoxylum , notably in Zanthoxylum nitidum. This compound has an anti-malarial...

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Zanthoxylum nitidum

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the world.[citation needed] The plant contains the chemical compounds nitidine, toddalolactone, and chelerythrine. The essential oil, at least from some...

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Zanthoxylum rhoifolium

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of the plant also have antibacterial and fungicidal action. It contains nitidine, an alkaloid with anti-malarial action. It is of commercial value as a...

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Zanthoxylum

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Nigeria contains several types of alkaloids including benzophenanthridines (nitidine, dihydronitidine, oxynitidine, fagaronine, dihydroavicine, chelerythrine...

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C21H18NO4

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g/mol, exact mass: 348.1236 u) may refer to: Chelerythrine, an alkaloid Nitidine, an alkaloid This set index page lists chemical structure articles associated...

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Topoisomerase inhibitor

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(NSC 314622), which was made accidentally in an attempt to synthesize nitidine chloride, an anticancer agent that does not inhibit topoisomerases. Research...

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Zanthoxylum coco

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N-methylisocorydine, skimminianine, α-fagarine, fagarine-2, magnoflorine, nitidine, chelerythrine, berberine, palmatine and candicine have been isolated from...

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Zanthoxylum kwangsiense

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powdery substance, which tastes very bitter and numb. Contains alkaloids nitidine and oxynitidine; fresh leaves contain furfuraldehyde and cuspidiol, a derivative...

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Zanthoxylum gilletii

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in Africa. The fruits are used to produce the spice uzazi. The alkaloid nitidine can be isolated from the plant. The amide alkaloids N-(4-hydroxyphenethyl)octacosanamide...

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Patricia Steeg

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will lack this protein, so Steeg and her team synthesized a drug called nitidine analog that will locate cancerous cells and destroy them based on the amount...

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Ivan Addae Mensah

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Croton megalocarpus (1989) Structure and Anti-Hypertensive Properties of Nitidine Chloride from Fagara Species (1987) Larvicidal Effects of Six Amide Alkaloids...

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Zanthoxylum dipetalum

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contain several chemical compounds, including canthin-6-one, chelerythrine, nitidine, tembetarine, avicennol, xanthoxyletin, lupeol, hesperidin, sitosterol...

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Mark Cushman

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discovered serendipitously during a synthesis of the antileukemic agent nitidine chloride, can eradicate cancer cells. The seminal paper describing the...

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Zanthoxylum avicennae

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leaves contain alkaloids, including avicine, dihydroavicine, oxyavicine, nitidine, chelerythrine, magnoliflorine, δ-tembetarine, and candicine, as well as...

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Maurizio Del Poeta

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John R. (1999). "Comparison of In Vitro Activities of Camptothecin and Nitidine Derivatives against Fungal and Cancer Cells". Antimicrobial Agents and...

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Satinder Vir Kessar

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benzo[c]phenanthridine alkaloids. Synthesis of chelerythrine, decarine, and nitidine". Journal of Organic Chemistry. 53 (8): 1708–1713. doi:10.1021/jo00243a020...

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