NET1 information

NET1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3EO2, 4XH9
Identifiers
Aliases	NET1, ARHGEF8, NET1A, neuroepithelial cell transforming 1
External IDs	OMIM: 606450; MGI: 1927138; HomoloGene: 4283; GeneCards: NET1; OMA:NET1 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	5,459,056 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	3,968,220 bp
RNA expression pattern
	Top expressed in
	palpebral conjunctiva; ; pericardium; ; pylorus; ; cardia; ; urethra; ; superior surface of tongue; ; trigeminal ganglion; ; parotid gland; ; rectum; ; inferior ganglion of vagus nerve;
	Top expressed in
	lip; ; intestinal villus; ; esophagus; ; yolk sac; ; duodenum; ; maxillary prominence; ; ankle; ; ascending aorta; ; left lung lobe; ; colon;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	guanyl-nucleotide exchange factor activity; protein binding;
Cellular component	cytoplasm; cytosol; plasma membrane; nucleus; intracellular anatomical structure;
Biological process	cellular response to ionizing radiation; positive regulation of GTPase activity; myoblast migration; positive regulation of substrate adhesion-dependent cell spreading; regulation of Rho protein signal transduction; intracellular signal transduction; regulation of small GTPase mediated signal transduction; regulation of cell growth; signal transduction; cellular response to hydrogen peroxide; positive regulation of apoptotic process; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	10276
	56349
	ENSG00000173848
	ENSMUSG00000021215
	Q7Z628; Q5SQI7
	Q9Z206
	NM_001047160; NM_005863
	NM_001047159; NM_019671
	NP_001040625; NP_005854; NP_005854.2
	NP_001040624; NP_062645
	Wikidata
View/Edit Human	View/Edit Mouse

Neuroepithelial cell-transforming gene 1 protein is a protein that in humans is encoded by the NET1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000173848 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021215 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Chan AM, Takai S, Yamada K, Miki T (Jul 1996). "Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning". Oncogene. 12 (6): 1259–66. PMID 8649828.
^ "Entrez Gene: NET1 neuroepithelial cell transforming gene 1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000173848 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021215 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8649828-5] Chan AM, Takai S, Yamada K, Miki T (Jul 1996). "Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning". Oncogene. 12 (6): 1259–66. PMID 8649828.

[entrez-6] "Entrez Gene: NET1 neuroepithelial cell transforming gene 1".

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