NCR1 information

NCR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1OLL, 1P6F
Identifiers
Aliases	NCR1, CD335, LY94, NK-p46, NKP46, natural cytotoxicity triggering receptor 1
External IDs	OMIM: 604530; MGI: 1336212; HomoloGene: 3551; GeneCards: NCR1; OMA:NCR1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	54,916,140 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	4,348,163 bp
RNA expression pattern
	Top expressed in
	blood; ; spleen; ; bone marrow cells; ; monocyte; ; placenta; ; liver; ; right lobe of liver; ; lymph node; ; right lung; ; upper lobe of left lung;
	Top expressed in
	blood; ; morula; ; spleen; ; right lung lobe; ; submandibular gland; ; extensor digitorum longus muscle; ; uterus; ; upper arm; ; triceps brachii muscle; ; jejunum;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; SWI/SNF complex; membrane;
Biological process	cellular defense response; natural killer cell activation; signal transduction; regulation of immune response; regulation of natural killer cell mediated cytotoxicity;
	Sources:Amigo / QuickGO
Orthologs
	9437
	17086
ENSG00000273535; ENSG00000277629; ENSG00000273916; ENSG00000275156; ENSG00000277824;
	ENSG00000277334; ENSG00000278362; ENSG00000275637; ENSG00000274053; ENSG00000275521; ENSG00000275822; ENSG00000277442; ENSG00000189430; ENSG00000284113; ENSG00000273506; ENSG00000276450; ENSG00000278025; ENSG00000288651
	ENSMUSG00000062524
	O76036
	Q8C567
	NM_001145457; NM_001145458; NM_001242356; NM_001242357; NM_004829
	NM_010746; NM_001368364
	NP_001138929; NP_001138930; NP_001229285; NP_001229286; NP_004820
	NP_034876; NP_001355293
	Wikidata
View/Edit Human	View/Edit Mouse

Natural cytotoxicity triggering receptor 1 is a protein that in humans is encoded by the NCR1 gene.^[5]^[6] NCR1 has also been designated as CD335 (cluster of differentiation, NKP46, NKp46, NK-p46, and LY94.^[7]

^ ^a ^b ^c ENSG00000277629, ENSG00000273916, ENSG00000275156, ENSG00000277824, ENSG00000277334, ENSG00000278362, ENSG00000275637, ENSG00000274053, ENSG00000275521, ENSG00000275822, ENSG00000277442, ENSG00000189430, ENSG00000284113, ENSG00000273506, ENSG00000276450, ENSG00000278025, ENSG00000288651 GRCh38: Ensembl release 89: ENSG00000273535, ENSG00000277629, ENSG00000273916, ENSG00000275156, ENSG00000277824, ENSG00000277334, ENSG00000278362, ENSG00000275637, ENSG00000274053, ENSG00000275521, ENSG00000275822, ENSG00000277442, ENSG00000189430, ENSG00000284113, ENSG00000273506, ENSG00000276450, ENSG00000278025, ENSG00000288651 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000062524 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Pessino A, Sivori S, Bottino C, Malaspina A, Morelli L, Moretta L, Biassoni R, Moretta A (Sep 1998). "Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity". J Exp Med. 188 (5): 953–60. doi:10.1084/jem.188.5.953. PMC 3207313. PMID 9730896.
^ "Entrez Gene: NCR1 natural cytotoxicity triggering receptor 1".
^ "NCR1 natural cytotoxicity triggering receptor 1 [Homo sapiens (human)] - Gene - NCBI".

[refGRCh38Ensembl-1] ENSG00000277629, ENSG00000273916, ENSG00000275156, ENSG00000277824, ENSG00000277334, ENSG00000278362, ENSG00000275637, ENSG00000274053, ENSG00000275521, ENSG00000275822, ENSG00000277442, ENSG00000189430, ENSG00000284113, ENSG00000273506, ENSG00000276450, ENSG00000278025, ENSG00000288651 GRCh38: Ensembl release 89: ENSG00000273535, ENSG00000277629, ENSG00000273916, ENSG00000275156, ENSG00000277824, ENSG00000277334, ENSG00000278362, ENSG00000275637, ENSG00000274053, ENSG00000275521, ENSG00000275822, ENSG00000277442, ENSG00000189430, ENSG00000284113, ENSG00000273506, ENSG00000276450, ENSG00000278025, ENSG00000288651 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000062524 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9730896-5] Pessino A, Sivori S, Bottino C, Malaspina A, Morelli L, Moretta L, Biassoni R, Moretta A (Sep 1998). "Molecular cloning of NKp46: a novel member of the immunoglobulin superfamily involved in triggering of natural cytotoxicity". J Exp Med. 188 (5): 953–60. doi:10.1084/jem.188.5.953. PMC 3207313. PMID 9730896.

[entrez-6] "Entrez Gene: NCR1 natural cytotoxicity triggering receptor 1".

[7] "NCR1 natural cytotoxicity triggering receptor 1 [Homo sapiens (human)] - Gene - NCBI".

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