Protein-coding gene in the species Homo sapiens
NCOA7 Identifiers Aliases NCOA7 , ERAP140, ESNA1, NCOA7-AS, Nbla00052, Nbla10993, TLDC4, dJ187J11.3, nuclear receptor coactivator 7External IDs OMIM: 609752 MGI: 2444847 HomoloGene: 65245 GeneCards: NCOA7 Gene location (Human) Chr. Chromosome 6 (human)[1] Band 6q22.31-q22.32 Start 125,781,161 bp[1] End 125,932,034 bp[1]
Gene location (Mouse) Chr. Chromosome 10 (mouse)[2] Band 10|10 A4 Start 30,504,995 bp[2] End 30,679,322 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Brodmann area 23 pancreatic epithelial cell Brodmann area 46 middle temporal gyrus endothelial cell parietal pleura visceral pleura spinal ganglia pons cerebellar vermis
Top expressed in cervix ventral tegmental area dorsomedial hypothalamic nucleus medial vestibular nucleus subiculum superior colliculus blood dorsal tegmental nucleus paraventricular nucleus of hypothalamus piriform cortex
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
protein binding
nuclear receptor coactivator activity
Cellular component
intracellular anatomical structure
nucleus
Biological process
regulation of transcription, DNA-templated
transcription, DNA-templated
positive regulation of transcription by RNA polymerase II
negative regulation of cellular response to oxidative stress
negative regulation of peptidyl-cysteine S-nitrosylation
negative regulation of oxidative stress-induced neuron death
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) NM_001122842 NM_001199619 NM_001199620 NM_001199621 NM_001199622 NM_181782
NM_001111267 NM_172495 NM_001358841 NM_001358842
RefSeq (protein) NP_001116314 NP_001186548 NP_001186549 NP_001186550 NP_001186551 NP_861447
NP_001104737 NP_766083 NP_001345770 NP_001345771
Location (UCSC) Chr 6: 125.78 – 125.93 Mb Chr 10: 30.5 – 30.68 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Nuclear receptor coactivator 7 is a protein that in humans is encoded by the NCOA7 gene.[5] [6]
^ a b c GRCh38: Ensembl release 89: ENSG00000111912 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039697 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Shao W, Halachmi S, Brown M (Apr 2002). "ERAP140, a Conserved Tissue-Specific Nuclear Receptor Coactivator". Mol Cell Biol . 22 (10): 3358–72. doi:10.1128/MCB.22.10.3358-3372.2002. PMC 133794 . PMID 11971969.
^ "Entrez Gene: NCOA7 nuclear receptor coactivator 7".