negative regulation of cell population proliferation
positive regulation of timing of catagen
negative regulation of keratinocyte differentiation
negative regulation of transcription regulatory region DNA binding
embryonic limb morphogenesis
frontal suture morphogenesis
mammary gland epithelium development
BMP signaling pathway involved in heart development
enamel mineralization
ossification
anterior/posterior pattern specification
bone morphogenesis
regulation of transcription, DNA-templated
cellular response to growth factor stimulus
activation of meiosis
endochondral bone growth
wound healing, spreading of epidermal cells
BMP signaling pathway
embryonic digit morphogenesis
positive regulation of mesenchymal cell apoptotic process
multicellular organism development
embryonic hindlimb morphogenesis
negative regulation of CREB transcription factor activity
outflow tract morphogenesis
bone trabecula formation
wound healing
regulation of apoptotic process
chondrocyte development
osteoblast development
positive regulation of osteoblast differentiation
cranial suture morphogenesis
negative regulation of fat cell differentiation
branching involved in mammary gland duct morphogenesis
outflow tract septum morphogenesis
negative regulation of transcription, DNA-templated
osteoblast differentiation
epithelial to mesenchymal transition involved in endocardial cushion formation
positive regulation of BMP signaling pathway
signal transduction involved in regulation of gene expression
cellular response to estradiol stimulus
embryonic forelimb morphogenesis
embryonic nail plate morphogenesis
negative regulation of apoptotic process
cartilage development
stem cell differentiation
odontogenesis
transcription, DNA-templated
negative regulation of transcription by RNA polymerase II
embryonic morphogenesis
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4488
17702
Ensembl
ENSG00000120149
n/a
UniProt
P35548
Q03358
RefSeq (mRNA)
NM_002449 NM_001363626
NM_013601
RefSeq (protein)
NP_002440 NP_001350555
NP_038629
Location (UCSC)
Chr 5: 174.72 – 174.73 Mb
n/a
PubMed search
[2]
[3]
Wikidata
View/Edit Human
View/Edit Mouse
Homeobox protein MSX-2 is a protein that in humans is encoded by the MSX2 gene.[4][5][6]
^ abcGRCh38: Ensembl release 89: ENSG00000120149 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Takahashi C, Akiyama N, Matsuzaki T, Takai S, Kitayama H, Noda M (May 1996). "Characterization of a human MSX-2 cDNA and its fragment isolated as a transformation suppressor gene against v-Ki-ras oncogene". Oncogene. 12 (10): 2137–46. PMID 8668339.
^Kostrzewa M, Grady DL, Moyzis RK, Flöter L, Müller U (March 1996). "Integration of four genes, a pseudogene, thirty-one STSs, and a highly polymorphic STRP into the 7-10 Mb YAC contig of 5q34-q35". Human Genetics. 97 (3): 399–403. doi:10.1007/BF02185781. PMID 8786091. S2CID 12647370.
is intricately connected to other processes within the cell. Twist, Mshhomeobox2 (Msx2), and promyeloctic leukemia zinc-finger protein (PLZF) act upstream...
gene family on the long arm of chromosome 2. DLX2 has been shown to interact with DLX5, MSX1 and Mshhomeobox2. GRCh38: Ensembl release 89: ENSG00000115844...
(pancreatic and duodenal homeobox protein 1) is located in the nuclear periphery as a result of interaction with HDAC1 and 2, which results in downregulation...