Mitochondrial ribosomal protein L32 information

MRPL32
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3J7Y, 3J9M
Identifiers
Aliases	MRPL32, L32mt, MRP-L32, bMRP-59b, HSPC283, mitochondrial ribosomal protein L32
External IDs	OMIM: 611839; MGI: 2137226; HomoloGene: 32711; GeneCards: MRPL32; OMA:MRPL32 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	42,948,958 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	14,787,750 bp
RNA expression pattern
	Top expressed in
	oocyte; ; myocardium of left ventricle; ; cardia; ; pancreatic epithelial cell; ; right ventricle; ; renal medulla; ; pylorus; ; cardiac muscle tissue of right atrium; ; left adrenal gland; ; metanephros;
	Top expressed in
	interventricular septum; ; medial ganglionic eminence; ; migratory enteric neural crest cell; ; atrioventricular valve; ; olfactory epithelium; ; endocardial cushion; ; myocardium of ventricle; ; abdominal wall; ; soleus muscle; ; intercostal muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of ribosome; RNA binding;
Cellular component	mitochondrial inner membrane; large ribosomal subunit; ribosome; mitochondrial ribosome; mitochondrion; mitochondrial large ribosomal subunit;
Biological process	mitochondrial translational elongation; mitochondrial translational termination; protein biosynthesis;
	Sources:Amigo / QuickGO
Orthologs
	64983
	75398
	ENSG00000106591
	ENSMUSG00000015672
	Q9BYC8
	Q9DCI9
	NM_031903
	NM_029271
	NP_114109
	NP_083547
	Wikidata
View/Edit Human	View/Edit Mouse

39S ribosomal protein L32, mitochondrial is a protein that in humans is encoded by the MRPL32 gene.^[5]^[6]

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L32 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome Xp.^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106591 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000015672 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T (Sep 2001). "The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders". Genomics. 77 (1–2): 65–70. doi:10.1006/geno.2001.6622. PMID 11543634.
^ ^a ^b "Entrez Gene: MRPL32 mitochondrial ribosomal protein L32".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000106591 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000015672 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11543634-5] Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T (Sep 2001). "The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders". Genomics. 77 (1–2): 65–70. doi:10.1006/geno.2001.6622. PMID 11543634.

[entrez-6] "Entrez Gene: MRPL32 mitochondrial ribosomal protein L32".

Mitochondrial ribosomal protein L32 information

and 5 Related for: Mitochondrial ribosomal protein L32 information

Mitochondrial ribosomal protein L32

L32

Ribosomal protein

Ribosome

Peptide deformylase