A microtome (from the Greek mikros, meaning "small", and temnein, meaning "to cut") is a cutting tool used to produce extremely thin slices of material known as sections, with the process being termed microsectioning. Important in science, microtomes are used in microscopy for the preparation of samples for observation under transmitted light or electron radiation.
Microtomes use steel, glass or diamond blades depending upon the specimen being sliced and the desired thickness of the sections being cut. Steel blades are used to prepare histological sections of animal or plant tissues for light microscopy. Glass knives are used to slice sections for light microscopy and to slice very thin sections for electron microscopy. Industrial grade diamond knives are used to slice hard materials such as bone, teeth and tough plant matter for both light microscopy and for electron microscopy. Gem-quality diamond knives are also used for slicing thin sections for electron microscopy.
Microtomy is a method for the preparation of thin sections for materials such as bones, minerals and teeth, and an alternative to electropolishing and ion milling. Microtome sections can be made thin enough to section a human hair across its breadth, with section thickness between 50 nm and 100 μm.
A microtome (from the Greek mikros, meaning "small", and temnein, meaning "to cut") is a cutting tool used to produce extremely thin slices of material...
The laser microtome is an instrument used for non-contact sectioning of biological tissues or materials. It was developed by the Rowiak GmbH, a spin-off...
frozen to form hardened blocks. For light microscopy, a knife mounted in a microtome is used to cut tissue sections (typically between 5-15 micrometers thick)...
called a microtome, placed in a freezer. The cryostat is usually a stationary upright freezer, with an external wheel for rotating the microtome. The temperature...
surface tension concentration data and the Gibbs adsorption equation. The microtome blade method is used to determine the weight and molal concentration of...
provide a properly oriented sample sturdy enough for obtaining a thin microtome section(s) for the slide. Once the wax embedded block is finished, sections...
compound) is used to embed tissue samples prior to frozen sectioning on a microtome-cryostat. This process is undertaken so as to mount slices (sections)...
oncological surgery. The technical name for this procedure is cryosection. The microtome device that cold cuts thin blocks of frozen tissue is called a cryotome...
The Climate of London. In 1770 he is credited with the invention of the microtome, a machine for making extremely thin slices as used in slide-preparation...
under electron microscopy, sections should be from 20 to 30 nanometers. Microtome can be used in sectioning of sufficiently thin slices. If the objects...
slices than those cut in paraffin-embedded samples using a microtome). It is similar to a microtome but uses a vibrating blade to cut through tissue. The vibration...
editions of the journal were published by MIT Press until 2004 and by Microtome Publishing thereafter. From its inception, the journal received no revenue...
set in a mold with wax to cool and solidify. Sections are then cut on a microtome. Candle-making Wax carving Bicycle chain lubrication Coatings for waxed...
Study of small structures involved passing light through them and the microtome was invented to provide sufficiently thin slices of tissue to examine...
Pereira; Stuart M. Shieber (2005). Prolog and Natural Language Analysis. Microtome. Adam Lally; Paul Fodor (31 March 2011). "Natural Language Processing...
deli products. Microplane – used for the grating of various food items. Microtome – the laboratory-grade equivalent, for much finer slicing thicknesses...
frozen rapidly (cryofixation), then fractured by breaking (or by using a microtome) while maintained at liquid nitrogen temperature. The cold fractured surface...
before examination in the microscope. Samples may be sectioned (with a microtome) if information about the organism's internal ultrastructure is to be...
cutting are the knife and saw, or in medicine and science the scalpel and microtome. However, any sufficiently sharp object is capable of cutting if it has...
intercalated discs, when seen on histopathology, have two main causes: Microtome sectioning, thereby being a visual artifact. Forceful myocardial contraction...
replacing the water with paraffin, cutting it into very thin sections using a microtome, placing the sections on a microscope slide, staining the tissue using...
used as a decalcifying agent making it possible to cut sections using a microtome once the tissue sample is demineralised. EDTA is also known to inhibit...
regenerative capacity. The deeper layers, if reshaped by a laser or cut by a microtome, will remain that way permanently with only limited healing or remodelling...
microscope samples in plastic so they may be sectioned (sliced thin) with a microtome and then imaged. Durcupan is notable for refractive index nD20 of 1.654...
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