Global InformationMicrosporum nanum information
| Microsporum nanum | |
|---|---|
Scientific classification 
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| Domain: | Eukaryota |
| Kingdom: | Fungi |
| Division: | Ascomycota |
| Class: | Eurotiomycetes |
| Order: | Onygenales |
| Family: | Arthrodermataceae |
| Genus: | Microsporum |
| Species: | M. nanum
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| Binomial name | |
| Microsporum nanum C.A.Fuentes (1956)
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| Synonyms | |
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Microsporum nanum is a pathogenic fungus in the family Arthrodermataceae. It is a type of dermatophyte that causes infection in dead keratinized tissues such as skin, hair, and nails.[1][2] Microsporum nanum is found worldwide and is both zoophilic and geophilic. Animals such as pigs and sheep are the natural hosts for the fungus; however, infection of humans is also possible. Majority of the human cases reported are associated with pig farming. The fungus can invade the skin of the host; if it is scratched off by the infected animal, the fungus is still capable of reproducing in soil.[3]
When grown on Sabouraud's Dextrose agar at 25 °C, M. nanum produces a thin, powdery, and soft fibrous colony that appears white at the center becoming light yellowish-brown towards the colony margin. The reverse side appears brownish-orange in young colony and reddish-brown in older colony.[4][5] The mitochondrial genome of M. nanum consists of 15 protein-coding genes, 2 rRNAs, 25 tRNAs, one intron and one intronic ORF. Approximately 84% of the mitochondrial genome are the structural genes.[6] Microsporum nanum infections include tinea capitis, tinea corporis, tinea cruris, and tinea faciei.[3] Griseofulvin, clotrimazole, miconazole,[7] enilconazole[8] and many herbal treatments, such as extracts from Azadirachta indica,[9] essential oil from Curcuma longa[10] and Eucalyptus pauciflora[11] have been reported to be effective in inhibiting the fungus.
- ^ Ajello, Libero; Edith Varsavsky; Oliver J. Ginther; George Bubash (Nov–Dec 1964). "The natural history of Microsporum nanum". Mycologia. 56 (6): 873–884. doi:10.2307/3756652. JSTOR 3756652.
- ^ Weitzman, I; Summerbell, RC (April 1995). "The Dermatophytes". Clinical Microbiology Reviews. 8 (2): 240–259. doi:10.1128/CMR.8.2.240. PMC 172857. PMID 7621400.
- ^ a b Land, Geoffrey A (1997). Chapter 7 The Genus Microsporum. Korea: Star Publishing Company.
- ^ Fuentes. "Microsporum nanum Species". DoctorFungus. Retrieved 12 October 2013.
- ^ "Microsporum nanum". Mycology Online. Retrieved 1 November 2013.
- ^ Wu, Y; Yang J; Yang F; Liu T; Leng W; Chu Y; Jin Q (May 2009). "Recent dermatophyte divergence revealed by comparative and phylogenetic analysis of mitochondrial genomes". BMC Genomics. 10: 238. doi:10.1186/1471-2164-10-238. PMC 2693141. PMID 19457268.
- ^ Roller, JA; Westblom TU (November 1986). "Microsporum nanum infection in hog farmers". J Am Acad Dermatol. 15 (5 Pt 1): 935–9. doi:10.1016/s0190-9622(86)70252-1. PMID 3782533.
- ^ Garcia-Sanchez, A; Bazan, J; de Mendoza, JH; Martinez, R; Sanchez, S; de Mendoza, MH (March 2011). "Outbreak of ringworm in a traditional Iberian pig farm in Spain". Mycoses. 54 (2): 179–181. doi:10.1111/j.1439-0507.2009.01776.x.
- ^ Mahmoud, DA; Hassanein NM; Youssef KA; Abou Zeid MA (July 2011). "Antifungal activity of different neem leaf extracts and the nimonol against some important human pathogens". Braz J Microbiol. 42 (3): 1007–1016. doi:10.1590/S1517-83822011000300021. PMC 3768785. PMID 24031718.
- ^ Pandey, KP; Mishra RK; Kamran A; Mishra P; Bajaj AK; Dikshit A (Apr 2010). "Studies on antidermatophytic activity of waste leaves of Curcuma longa L." Physiol Mol Biol Plants. 16 (2): 177–185. doi:10.1007/s12298-010-0019-5. PMC 3550606. PMID 23572967.
- ^ Shahi, SK; Shukla AC; Bajaj AK; Banerjee U; Rimek D; Midgely G; Dikshit A (Jan–Feb 2000). "Broad spectrum herbal therapy against superficial fungal infections". Skin Pharmacol Appl Skin Physiol. 13 (1): 60–64. doi:10.1159/000029909. PMID 10657767.