Global InformationMetaboLights information
| Content | |
|---|---|
| Description | Metabolomics database |
| Data types captured | metabolites from different species, metabolite structure, chemical properties, synonyms, experimental protocols, taxonomy, reactions, pathways, NMR spectra, mass spectra |
| Contact | |
| Research center | European Molecular Biology Laboratory |
| Laboratory |  European Bioinformatics Institute |
| Primary citation | PMID 23109552 |
| Access | |
| Website | http://www.ebi.ac.uk/metabolights/ |
| Download URL | http://www.ebi.ac.uk/metabolights/download |
| Tools | |
| Web | MetaboLights Website |
| Miscellaneous | |
| Data release frequency | live |
| Curation policy | Manually curated |
MetaboLights[1] is a data repository founded in 2012 for cross-species and cross-platform metabolomic studies that provides primary research data and meta data for metabolomic studies as well as a knowledge base for properties of individual metabolites.[2][3][4] The database is maintained by the European Bioinformatics Institute (EMBL-EBI) and the development is funded by Biotechnology and Biological Sciences Research Council (BBSRC).[5][6] As of July 2018, the MetaboLights browse functionality consists of 383 studies, two analytical platforms, NMR spectroscopy and mass spectrometry.[7]
Semantic annotation is based on various ontologies and controlled vocabularies, including the BRENDA tissue ontology and the NCBI taxonomy. The metabolite structure data is linked to chemical databases, including ChemSpider, PubChem, and ChEBI. Links to metabolite databases, however, seem to be missing.
MetaboLights consists of two components:
- a repository, that enables the metabolomic community to share experimental findings, data and protocols for any metabolomic study. (Fig. 1-2)
- a reference layer of individual metabolite compounds and their reference spectra including additional information on their biological roles, locations, concentrations and raw data from metabolomic experiments. (Fig. 3)
- ^ Kenneth Haug; Reza M. Salek; Pablo Conesa; et al. (January 2013). "MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data". Nucleic Acids Research. 41 (Database issue): D781-6. doi:10.1093/NAR/GKS1004. ISSN 0305-1048. PMC 3531110. PMID 23109552. Wikidata Q27818909.
- ^ Susanna-Assunta Sansone; Philippe Rocca-Serra; Dawn Field; et al. (27 January 2012). "Toward interoperable bioscience data". Nature Genetics. 44 (2): 121–6. doi:10.1038/NG.1054. ISSN 1061-4036. PMC 3428019. PMID 22281772. Wikidata Q28090939.
- ^ Haug, Kenneth; Salek, Reza M.; Conesa, Pablo; Mahendraker, Tejasvi; Williams, Mark; Griffin, Julian L.; Steinbeck, Christoph. "MetaboLights - The new EBI Metabolomics database". No. 19. MetaboNews. Retrieved 5 May 2015.
- ^ Reza M. Salek; Kenneth Haug; Pablo Conesa; et al. (2013). "The MetaboLights repository: curation challenges in metabolomics". Database. 2013 (0): bat029. doi:10.1093/DATABASE/BAT029. ISSN 1758-0463. PMC 3638156. PMID 23630246. Wikidata Q28707581.
- ^ BBSRC Grant BB/I000933/1 "MetaboLights: Creating the missing Metabolomics community resource", http://www.bbsrc.ac.uk/research/grants/grants/AwardDetails.aspx?FundingReference=BB/I000933/1
- ^ £30,000 Boost For UK-China Metabolomics Data Sharing, Asian Scientist Newsroom, 2015, retrieved 2015-06-11
- ^ "Browse".