Global InformationMensacarcin information
Mensacarcin is a highly oxygenated polyketide first isolated from soil-dwelling Streptomyces bottropensis bacteria.[1][2]
The molecule is a secondary metabolite, and can be obtained in large amounts from its producing organism.[2]
Due to its unique properties it is an important model for drug development against melanoma and other cancers.
- ^ Plitzko, Birte; Kaweesa, Elizabeth N.; Loesgen, Sandra (26 October 2017). "The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells". The Journal of Biological Chemistry. 292 (51): 21102–21116. doi:10.1074/jbc.M116.774836. PMC 5743083. PMID 29074620.
- ^ a b Lundeberg, Steve (4 January 2018). "Dirt-dwelling microbe produces potential anti-melanoma weapon". phys.org. Science X. Retrieved 5 January 2018.