Global Information Lookup Global Information

Meldonium information


Meldonium
Clinical data
Trade namesMildronate, Mildronāts
Other namesTHP, MET-8 Mildronāts or Quaterine
ATC code
  • C01EB22 (WHO)
Legal status
Legal status
  • US: Unscheduled
Identifiers
IUPAC name
  • 2-(2-Carboxylato-ethyl)-1,1,1-trimethylhydrazinium
CAS Number
  • 76144-81-5 checkY
  • dihydrate: 86426-17-7 checkY
PubChem CID
  • 123868
ChemSpider
  • 110405 checkY
UNII
  • 73H7UDN6EC
  • dihydrate: 22DC15W645 checkY
KEGG
  • D10504
ChEBI
  • CHEBI:131843 checkY
CompTox Dashboard (EPA)
  • DTXSID10997497 Edit this at Wikidata
ECHA InfoCard100.110.108 Edit this at Wikidata
Chemical and physical data
FormulaC6H14N2O2
Molar mass146.190 g·mol−1
3D model (JSmol)
  • Interactive image
Solubility in water>40 mg/mL mg/mL (20 °C)
SMILES
  • C[N+](C)(C)NCCC(=O)[O-]
InChI
  • InChI=1S/C6H14N2O2/c1-8(2,3)7-5-4-6(9)10/h7H,4-5H2,1-3H3
  • Key:PVBQYTCFVWZSJK-UHFFFAOYSA-N

Meldonium (INN; trade name Mildronate, among others) is a limited-market pharmaceutical, developed in 1970 by Ivars Kalviņš at the USSR Latvia Institute of Organic Synthesis, and now manufactured by the Latvian pharmaceutical company Grindeks and several generic manufacturers. It is primarily distributed in Eastern European countries as an anti-ischemia medication.[1]

Since 1 January 2016, it has been on the World Anti-Doping Agency (WADA) list of substances banned from use by athletes.[2] Meldonium can be used as a metabolic modulator, changing how some hormones accelerate or slow down enzymatic reactions in the body. However, there are debates over its use as an athletic performance enhancer. Some athletes are known to have used meldonium before it was banned, most notably Maria Sharapova.[3] Nevertheless, many athletes have been suspended or disqualified officially in relation to this drug.

  1. ^ "Grindeks: We Believe that Meldonium Should not be Included in the List of Banned Substances in Sport". Grindeks. 9 March 2016. Archived from the original on 12 March 2016. Retrieved 9 March 2016.
  2. ^ "Prohibited List". World Anti-Doping Agency. 14 November 2013. Archived from the original on 12 July 2017. Retrieved 9 March 2016.
  3. ^ "All About Meldonium, the Banned Drug Used by Sharapova". New York Times. Associated Press. 8 March 2016. Retrieved 8 March 2016.

and 25 Related for: Meldonium information

Request time (Page generated in 0.5754 seconds.)

Meldonium

Last Update:

Meldonium (INN; trade name Mildronate, among others) is a limited-market pharmaceutical, developed in 1970 by Ivars Kalviņš at the USSR Latvia Institute...

Word Count : 4893

Maria Sharapova

Last Update:

failed a drug test at the 2016 Australian Open, testing positive for meldonium, a substance that had been banned (effective 1 January 2016) by the World...

Word Count : 21831

Doping in figure skating

Last Update:

sleek, which is required for an athlete to be competitive. PEDs such as meldonium, pseudoephedrine and torasemide have been used in the sport of figure...

Word Count : 3229

Oleg Verniaiev

Last Update:

all-around champion. Verniaiev tested positive for the banned substance meldonium in an out-of-competition test in August 2020. He received a four-year...

Word Count : 1634

Islam Makhachev

Last Update:

out-of-competition drug screening, testing positive for the banned anti-ischemic meldonium. USADA lifted Makhachev's suspension after a hearing on 2 July 2016 determined...

Word Count : 4441

2023 Asian Athletics Championships

Last Update:

of Uzbekistan, who originally clocked 52.95 seconds, failed a test for meldonium, disqualifying her from the competition and promoting the other competitors...

Word Count : 354

Ultimate Fighting Championship

Last Update:

Hydrochlorothiazide for diuretic agent to mask potential doping evidence, Meldonium for stimulating the production of red blood cells which would increase...

Word Count : 31356

Pavel Kulizhnikov

Last Update:

concentration of meldonium was below the threshold. The International Skating Union's Official Statement was quoted: "In the case of Meldonium, the WADA recognized...

Word Count : 1717

Grindeks

Last Update:

Diclofenac gel Loperamide Risperidone Zopiclone Bisacodyl Digoxin Meldonium Phosphate (Mildronate®) Rivaroxaban Bromhexine Dimetindene Memantine hydrochloride...

Word Count : 1361

Olga Abramova

Last Update:

team. On 10 January 2016 she failed a drug test when meldonium was found in her doping test. Meldonium became illegal to use on 1 January 2016. Ольга Абрамова:...

Word Count : 172

Nikolai Kuksenkov

Last Update:

Kuksenkov positive for meldonium". uatoday.tv. Retrieved 3 April 2016. "Top Russian gymnast Nikolai Kuksenkov fails drug test as meldonium found in sample"...

Word Count : 926

Alexander Povetkin

Last Update:

tested positive for the banned substance meldonium. Promotor Andrei Ryabinsky added that Povetkin did take meldonium last year, but stopped before it was...

Word Count : 9721

Sodium polydihydroxyphenylene thiosulfonate

Last Update:

2,4-dihydroxyphenylene with a thiosulphonate group joined at the end. Meldonium Trimetazidine Novikov VE, Levchenkova OS, Ivantsova EN, Vorobieva VV (2019)...

Word Count : 520

Igor Mikhalkin

Last Update:

defense against Bois, Mikhalkin tested positive and admitted to taking meldonium, a substance banned by WADA and was stripped by the EBU. He was also banned...

Word Count : 401

Roman Kryklia

Last Update:

Champions 2016, testing positive for two banned substances, including meldonium and clenbuterol. He was suspended for 4 years by National Anti-Doping...

Word Count : 2511

C6H14N2O2

Last Update:

formula C6H14N2O2 (molar mass: 146.19 g/mol) may refer to: Lysine β-Lysine Meldonium 3-Methylornithine N-Methylornithine This set index page lists chemical...

Word Count : 56

UFC 259

Last Update:

out-of-competition drug screening, testing positive for the banned anti-ischemic meldonium. Randy Costa was expected to face Trevin Jones in a bantamweight bout...

Word Count : 1079

Semion Elistratov

Last Update:

concentration of meldonium was below the threshold. The International Skating Union's Official Statement was quoted: "In the case of Meldonium, the WADA recognized...

Word Count : 610

Carnitine

Last Update:

Gamma-butyrobetaine dioxygenase Glycine Propionyl-l-Carnitine (GPLC) Meldonium Systemic primary carnitine deficiency "L-Carnitine". Micronutrient Information...

Word Count : 3278

Doping in Russia

Last Update:

fail drug tests in March and May respectively, both testing positive for Meldonium. Russian-Finnish footballer Roman Eremenko would also fail a drugs test...

Word Count : 18181

Deontay Wilder

Last Update:

tested positive for the banned substance meldonium. Promoter Andrei Ryabinsky added that Povetkin did take meldonium in 2015, but stopped before it was banned...

Word Count : 14096

List of doping cases in cycling

Last Update:

was announced that Eduard Vorganov was suspended for a positive test to meldonium. On the 12 March, British road cyclist Simon Yates tested positive for...

Word Count : 39705

Drew Dober

Last Update:

out-of-competition drug screening, testing positive for the banned anti-ischemic meldonium. The match was cancelled. A rescheduled bout with Erik Koch was expected...

Word Count : 2909

Varvara Lepchenko

Last Update:

the WTA Tour in 2016 after testing positive for the heart medication meldonium, although she was found to "bear no fault or negligence" by the International...

Word Count : 6845

Nadezhda Sergeeva

Last Update:

Sergeeva had failed a drug test, testing positive for meldonium. The test showed less than 1 µg meldonium. Sergeeva and teammate Anastasia Kocherzhova won...

Word Count : 451

PDF Search Engine © AllGlobal.net