A melanotroph (or melanotrope) is a cell in the pituitary gland that generates melanocyte-stimulating hormone (α‐MSH) from its precursor pro-opiomelanocortin. Chronic stress can induce the secretion of α‐MSH in melanotrophs and lead to their subsequent degeneration.[1]
^Ogawa, Tokiko; Shishioh‐Ikejima, Nobue; Konishi, Hiroyuki; Makino, Tetsuya; Sei, Hiroyoshi; Kiryu‐Seo, Sumiko; Tanaka, Masaaki; Watanabe, Yasuyoshi; Kiyama, Hiroshi. "Chronic stress elicits prolonged activation of α‐MSH secretion and subsequent degeneration of melanotroph". Journal of Neurochemistry. 109 (5). doi:10.1111/j.1471-4159.2009.06057.x.
A melanotroph (or melanotrope) is a cell in the pituitary gland that generates melanocyte-stimulating hormone (α‐MSH) from its precursor pro-opiomelanocortin...
hormones of the anterior pituitary and releasing them into the bloodstream. Melanotrophs (also, Melanotropes) are another type of chromophobe which secrete...
in the median sagittal plane Head and neck anatomy Chromophobe cell Melanotroph Chromophil Acidophil cell Basophil cell Oxyphil cell (parathyroid) Neuroendocrine...
*Produced only in pregnancy by the developing embryo. Chromophobe cell Melanotroph Chromophil Acidophil cell Oxyphil cell Oxyphil cell (parathyroid) Pituitary...
addition to synthesis in the corticotropes, POMC is also synthesized in melanotroph cells, the arcuate nucleus of the hypothalamus, and melanocytes. POMC...
increased insulin secretion due to higher levels of CLIP produced by melanotrophs, and to cause insulin resistance secondary to hyperadrenocorticism. Due...
pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. The Tpit gene is responsible for a neonatal form of acth deficiency...
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