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Masayo Takahashi information


Masayo Takahashi
Born (1961-06-23) June 23, 1961 (age 63)
Osaka, Japan
NationalityJapanese
Alma materKyoto University
Known forClinical application of Induced pluripotent stem cell research
Scientific career
FieldsStem cell research
Ophthalmology
InstitutionsRiken Institute
Kyoto University
Salk Institute

Masayo Takahashi (高橋 政代, Takahashi Masayo, born June 23, 1961) is a Japanese medical physician, ophthalmologist and stem cell researcher.

Takahashi serves as a project research leader at the Riken Center for Developmental Biology in Kobe focusing on the clinical application of iPS Cell (induced Pluripotent Stem Cell) technology on macular degeneration. In 2014, Takahashi was named by British science journal Nature as one of "five to watch" global scientists for her groundbreaking work in regenerative medicine.[1]

In March 2017 a team led by Takahashi completed the first successful transplant of iPS-derived retinal cells into the eye of a patient suffering from advanced wet age-related macular degeneration.[2] During the surgery the patient received a transplant of approximately 250,000 retinal pigment epithelial cells into the eye generated from donor-derived iPSCs. Results of this landmark study were published in the New England Journal of Medicine.[3]

  1. ^ "TEDxTokyo". TEDxTokyo. Retrieved 6 September 2017.
  2. ^ "First donor iPSC-derived RPE cell transplantation in AMD patient". RIKEN Center for Developmental Biology. 4 April 2017. Retrieved 6 September 2017.
  3. ^ Mandai, Michiko; Watanabe, Akira; Kurimoto, Yasuo; Hirami, Yasuhiko; Morinaga, Chikako; Daimon, Takashi; Fujihara, Masashi; Akimaru, Hiroshi; Sakai, Noriko (2017-03-16). "Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration". New England Journal of Medicine. 376 (11): 1038–1046. doi:10.1056/nejmoa1608368. ISSN 0028-4793. PMID 28296613. S2CID 27993960.

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