Mafoprazine information

Mafoprazine
Clinical data
Trade names	Mafropan
AHFS/Drugs.com	Monograph
Identifiers
	IUPAC name N-[4-[3-[4-(2-fluorophenyl)piperazin-1-yl]propoxy]-3-methoxyphenyl]acetamide;
CAS Number	80428-29-1 ;
PubChem CID	71241;
ChemSpider	64374 ;
UNII	D7UUO54C6N;
KEGG	C18361 ;
ChEMBL	ChEMBL2105101 ;
CompTox Dashboard (EPA)	DTXSID50230310 ;
Chemical and physical data
Formula	C22H28FN3O3
Molar mass	401.482 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COC1=C(OCCCN2CCN(CC2)C3=C(F)C=CC=C3)C=CC(NC(C)=O)=C1;
	InChI InChI=1S/C22H28FN3O3/c1-17(27)24-18-8-9-21(22(16-18)28-2)29-15-5-10-25-11-13-26(14-12-25)20-7-4-3-6-19(20)23/h3-4,6-9,16H,5,10-15H2,1-2H3,(H,24,27) ; Key:PHOCQBYGUQPMIB-UHFFFAOYSA-N ;

Mafoprazine is an antipsychotic of the phenylpiperazine class which is used in veterinary medicine.^[1] Intramuscular injections of mafoprazine mesylate are used for the sedation of pigs either on its own,^[2] or in combination with sodium pentobarbital^[3] or thiopental.^[4]

^ "Mafoprazine | Chemical Substance Information | J-GLOBAL". jglobal.jst.go.jp.
^ Heishima, Kazuki; Kuo, Kendon; Kimura, Masashi; Mori, Takashi (2019). "Animal Lymphocyte Metaphase Chromosome Preparation". Radiation Cytogenetics. Methods in Molecular Biology. Vol. 1984. pp. 7–22. doi:10.1007/978-1-4939-9432-8_2. ISBN 978-1-4939-9430-4. PMID 31267415. S2CID 195787061.
^ Azizi, AFN; Miyazaki, R; Yumito, T; Ohashi, Y; Uno, S; Miyajima, U; Kumamoto, M; Uchiyama, S; Yasuda, M (1 January 2018). "Effect of maternal supplementation with seaweed powder on immune status of liver and lymphoid organs of piglets". The Journal of Veterinary Medical Science. 80 (1): 8–12. doi:10.1292/jvms.17-0537. PMC 5797852. PMID 29142150.
^ Umeyama, Kazuhiro; Watanabe, Kota; Watanabe, Masahito; Horiuchi, Keisuke; Nakano, Kazuaki; Kitashiro, Masateru; Matsunari, Hitomi; Kimura, Tokuhiro; Arima, Yoshimi; Sampetrean, Oltea; Nagaya, Masaki; Saito, Masahiro; Saya, Hideyuki; Kosaki, Kenjiro; Nagashima, Hiroshi; Matsumoto, Morio (14 April 2016). "Generation of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblasts". Scientific Reports. 6 (1): 24413. Bibcode:2016NatSR...624413U. doi:10.1038/srep24413. PMC 4830947. PMID 27074716. S2CID 22352477.

[1] "Mafoprazine | Chemical Substance Information | J-GLOBAL". jglobal.jst.go.jp.

[2] Heishima, Kazuki; Kuo, Kendon; Kimura, Masashi; Mori, Takashi (2019). "Animal Lymphocyte Metaphase Chromosome Preparation". Radiation Cytogenetics. Methods in Molecular Biology. Vol. 1984. pp. 7–22. doi:10.1007/978-1-4939-9432-8_2. ISBN 978-1-4939-9430-4. PMID 31267415. S2CID 195787061.

[3] Azizi, AFN; Miyazaki, R; Yumito, T; Ohashi, Y; Uno, S; Miyajima, U; Kumamoto, M; Uchiyama, S; Yasuda, M (1 January 2018). "Effect of maternal supplementation with seaweed powder on immune status of liver and lymphoid organs of piglets". The Journal of Veterinary Medical Science. 80 (1): 8–12. doi:10.1292/jvms.17-0537. PMC 5797852. PMID 29142150.

[4] Umeyama, Kazuhiro; Watanabe, Kota; Watanabe, Masahito; Horiuchi, Keisuke; Nakano, Kazuaki; Kitashiro, Masateru; Matsunari, Hitomi; Kimura, Tokuhiro; Arima, Yoshimi; Sampetrean, Oltea; Nagaya, Masaki; Saito, Masahiro; Saya, Hideyuki; Kosaki, Kenjiro; Nagashima, Hiroshi; Matsumoto, Morio (14 April 2016). "Generation of heterozygous fibrillin-1 mutant cloned pigs from genome-edited foetal fibroblasts". Scientific Reports. 6 (1): 24413. Bibcode:2016NatSR...624413U. doi:10.1038/srep24413. PMC 4830947. PMID 27074716. S2CID 22352477.

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