Protein-coding gene in the species Homo sapiens
MZB1 Identifiers Aliases MZB1 , MEDA-7, PACAP, pERp1, marginal zone B and B1 cell specific proteinExternal IDs OMIM: 609447; MGI: 1917066; HomoloGene: 12333; GeneCards: MZB1; OMA:MZB1 - orthologs Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5q31.2 Start 139,387,467 bp[1] End 139,390,081 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 B2 Start 35,780,320 bp[2] End 35,782,420 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in thymus spleen lymph node appendix rectum mucosa of transverse colon tonsil bone marrow cells trachea duodenum
Top expressed in spleen ileum jejunum bone marrow colon thymus duodenum granulocyte embryo pharynx
More reference expression data
BioGPS
Gene ontology Molecular function Cellular component
cytoplasm
extracellular region
endoplasmic reticulum lumen
endoplasmic reticulum
endoplasmic reticulum chaperone complex Biological process
integrin activation
regulation of cell population proliferation
positive regulation of cell population proliferation
apoptotic process
regulation of B cell proliferation
regulation of insulin receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 5: 139.39 – 139.39 Mb Chr 18: 35.78 – 35.78 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Marginal zone B and B1 cell-specific protein is a protein that in humans is encoded by the MZB1 gene.[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000170476 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024353 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Entrez Gene: Marginal zone B and B1 cell-specific protein".
Last Update: 2022-10-17T09:50:11Z
and B1 cell-specific protein is a protein that in humans is encoded by the MZB1 gene. GRCh38: Ensembl release 89: ENSG00000170476 – Ensembl, May 2017 GRCm38:...
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Last Update: 2024-03-28T22:55:32Z
MTRR: 5-methyltetrahydrofolate-homocysteine methyltransferase reductase MZB1 : Marginal zone B and B1 cell-specific protein NIPBL: Nipped-B homolog (Drosophila)...
Word Count : 2298
Last Update: 2023-12-03T10:22:31Z
involves chaperone proteins including binding immunoglobulin protein (BiP) and MZB1 each sequentially recruiting distinct factors of the polymerized antibody...
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Last Update: 2024-04-30T08:47:55Z
meiotic chromosome synapsis may be involved in meiotic double strand breaks MZB1 -marginal zone B and B1 cell-specific protein associates with immunoglobulin...
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