dynamin family protein polymerization involved in mitochondrial fission
membrane fusion
defense response to virus
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
4599
17858
Ensembl
ENSG00000157601
ENSMUSG00000023341
UniProt
P20591
Q9WVP9
RefSeq (mRNA)
NM_001144925 NM_001178046 NM_001282920 NM_002462
NM_013606
RefSeq (protein)
NP_001138397 NP_001171517 NP_001269849 NP_002453
NP_038634
Location (UCSC)
Chr 21: 41.42 – 41.47 Mb
Chr 16: 97.34 – 97.36 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Interferon-induced GTP-binding protein Mx1 is a protein that in humans is encoded by the MX1 gene.[5][6]
In mice, the interferon-inducible Mx protein is responsible for a specific antiviral state against influenza virus infection. Furthermore, the human orthologue MxA is a major determinant for influenza viruses of animal origin.[7] The protein encoded by this gene is similar to the mouse protein as determined by its antigenic relatedness, induction conditions, physicochemical properties, and amino acid analysis. This cytoplasmic protein is a member of both the dynamin superfamily and the family of large GTPases.[6]
^ abcGRCh38: Ensembl release 89: ENSG00000157601 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000023341 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Haller O, Staeheli P, Kochs G (Jul 2007). "Interferon-induced Mx proteins in antiviral host defense". Biochimie. 89 (6–7): 812–8. doi:10.1016/j.biochi.2007.04.015. PMID 17570575.
Interferon-induced GTP-binding protein Mx1 is a protein that in humans is encoded by the MX1 gene. In mice, the interferon-inducible Mx protein is responsible...
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across Europe. In the UK-based MX Nationals series Kullas has taken the MX1 title three times as well as winning the overall Pro Fastest 40 ranking in...
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