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MOMS Trial information


The MOMS Trial was a clinical trial that studied treatment of a birth defect called myelomeningocele, which is the most severe form of spina bifida. The study looked at prenatal (before birth) and postnatal (after birth) surgery to repair this defect. The first major phase concluded that prenatal surgery had strong, long-term benefits and some risks.[1]

The name of the trial stands for Management of Myelomeningocele Study. It was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) and was done by The Children's Hospital of Philadelphia, the University of California, San Francisco, Vanderbilt University Medical Center in Nashville and the George Washington University in Washington, D.C.

  1. ^ Adzick, N. Scott; Thom, Elizabeth A.; Spong, Catherine Y.; Brock, John W.; Burrows, Pamela K.; Johnson, Mark P.; Howell, Lori J.; Farrell, Jody A.; Dabrowiak, Mary E. (2011-03-17). "A randomized trial of prenatal versus postnatal repair of myelomeningocele". The New England Journal of Medicine. 364 (11): 993–1004. doi:10.1056/NEJMoa1014379. ISSN 1533-4406. PMC 3770179. PMID 21306277.

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