Lysinibacillus sphaericus (previously known as Bacillus sphaericus)[1] is a Gram-positive, mesophilic, rod-shaped bacterium commonly found on soil. It can form resistant endospores that are tolerant to high temperatures, chemicals and ultraviolet light and can remain viable for long periods of time. It is of particular interest to the World Health Organization due to the larvicide effect of some strains against two mosquito genera (Culex and Anopheles),[2] more effective than Bacillus thuringiensis, frequently used as a biological pest control. L. sphaericus cells in a vegetative state are also effective against Aedes aegypti larvae,[3] an important vector of yellow fever and dengue viruses.
A bacterium similar to this species was found in a 25-million-year-old amber from the Dominican Republic. The endospore was successfully revived.[4]
^Ahmed, Iftikhar; Yokota, Akira; Yamazoe, Atsushi; Fujiwara, Toru (2007). "Proposal of Lysinibacillus boronitolerans gen. nov. sp. nov., and transfer of Bacillus fusiformis to Lysinibacillus fusiformis comb. nov. and Bacillus sphaericus to Lysinibacillus sphaericus comb. nov". International Journal of Systematic and Evolutionary Microbiology. 57 (5): 1117–1125. doi:10.1099/ijs.0.63867-0. PMID 17473269.
^Berry, Colin (2012-01-01). "The bacterium, Lysinibacillus sphaericus, as an insect pathogen". Journal of Invertebrate Pathology. 109 (1): 1–10. doi:10.1016/j.jip.2011.11.008. PMID 22137877.
^Santana-Martinez, JC; Silva, JJ; Dussan, J (February 2019). "Efficacy of Lysinibacillus sphaericus against mixed-cultures of field-collected and laboratory larvae of Aedes aegypti and Culex quinquefasciatus". Bulletin of Entomological Research. 109 (1): 111–118. doi:10.1017/S0007485318000342. PMID 29784071. S2CID 29162148.
^Cano, RJ; Borucki, MK (19 May 1995). "Revival and identification of bacterial spores in 25- to 40-million-year-old Dominican amber". Science. 268 (5213): 1060–4. doi:10.1126/science.7538699. PMID 7538699.
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