American actor and singer Chris BurkeBritish actor Tommy Jessop (right) with his brother WilliamSpanish actor Pablo Pineda, the first European with Down syndrome to complete a university degreeBritish actress Paula Sage receiving her BAFTA award with Brian CoxEnglish disability rights activist Heidi Crowter
This is a list of people with Down syndrome, a condition also known as Down's syndrome or trisomy 21. Down syndrome is a genetic disorder caused by the presence of all or part of a third copy of chromosome 21.[1] It is typically associated with developmental delays, characteristic physical features, and mild to moderate intellectual disability.[2] The average IQ of a young adult with Down syndrome is 50, equivalent to the mental age of an 8- or 9-year-old child, but this number varies widely.[3] At the same time, they enjoy a rich social and emotional awareness.[4] Down syndrome is the most common chromosome abnormality in humans,[3] occurring in about one per 1000 babies born each year.[2]
^Patterson, D (Jul 2009). "Molecular genetic analysis of Down syndrome". Human Genetics. 126 (1): 195–214. doi:10.1007/s00439-009-0696-8. PMID 19526251. S2CID 10403507.
^ abWeijerman, ME; de Winter, JP (Dec 2010). "Clinical practice. The care of children with Down syndrome". European Journal of Pediatrics. 169 (12): 1445–52. doi:10.1007/s00431-010-1253-0. PMC 2962780. PMID 20632187.
^ abMalt, EA; Dahl, RC; Haugsand, TM; Ulvestad, IH; Emilsen, NM; Hansen, B; Cardenas, YE; Skøld, RO; Thorsen, AT; Davidsen, EM (Feb 5, 2013). "Health and disease in adults with Down syndrome". Tidsskrift for den Norske Laegeforening. 133 (3): 290–4. doi:10.4045/tidsskr.12.0390. PMID 23381164.
^L. Hippolyte, K. Iglesias, M. Van der Linden & K. Barisnikov (August 2010). "Social reasoning skills in adults with Down syndrome: the role of language, executive functions and socio-emotional behaviour". Journal of Intellectual Disability Research (doi: 10.1111/j.1365-2788.2010.01299.x): 1.
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