University College London College of the Pharmaceutical Society
Known for
refinement of the chemotherapeutic index
Awards
Manson Medal (1992)
Scientific career
Fields
protozoology
Institutions
Wellcome Bureau of Scientific Research Wellcome Laboratories of Tropical Medicine Nuffield Laboratories for Comparative Medicine
Leonard George Goodwin CMG FRS[1] (11 July 1915 – 25 November 2008) was a British protozoologist noted for his work on testing the effectiveness of chemical compounds in treating tropical diseases.[2] He was born in London to a shoe shop manager, and became interested in nature thanks to holidays spent with his grandfather, a gamekeeper, and his uncle, a pharmacist. He was educated at William Ellis School before being accepted into University College London to study botany and zoology. After graduating he went to the College of the Pharmaceutical Society and studied pharmacy, graduating in 1935. He became a demonstrator at the college under J H Burn and at his urging took further degrees in medicine and physiology.
The start of World War II saw the College evacuated, leaving Goodwin to find a new job. He started work at the Wellcome Bureau of Scientific Research but was called up for military service with the Royal Tank Regiment soon afterwards. After only a few days of training he was returned to Wellcome to work on tropical diseases, something considered 'vital war work' which excused him from military service.[2] One of the important problems he was dealing with at the time was trying to find a way of preventing troops being infected with leishmaniasis, which was affecting large numbers of troops in Sicily at the time. The standard way of calculating the dosage of drug to give a person was the 'chemotherapeutic index', an index between the minimum dosage to cure an infection and the point at which the drug would kill the patient. Goodwin's attempt at refining the index by testing the drugs on European hamsters failed because they were already resistant to leishmaniasis; instead he got a scientist in Jerusalem to send him some Syrian hamsters to test the drugs on.[2]
The research showed that Pentostam was the least toxic and most effective drug available to treat the disease, and it was issued to troops within a year. Goodwin later claimed that the Syrian hamsters used as pets in the United Kingdom were for the most part descended from the colony he had bred, and credited himself with introducing the use of hamsters as pets.[2] He continued working at the Wellcome Bureau of Scientific Research until 1958, when he became director of the Wellcome Laboratories of Tropical Medicine. In 1964 he became head of the Nuffield Laboratories for Comparative Medicine, staying there until 1980. During this time he conducted research into anticoagulants, trypanosomiasis (sleeping sickness) and arteriosclerosis. In 1976 he was elected a Fellow of the Royal Society,[2] and in the 1977 New Year Honours was appointed Companion of the Order of St Michael and St George (CMG) "for services to the study of tropical diseases".[3]
^Peaker, Malcolm; Ogilvie, Dame Bridget M. (2021). "Leonard George Goodwin. 11 July 1915—25 November 2008". Biographical Memoirs of Fellows of the Royal Society. 71: 213–227. doi:10.1098/rsbm.2020.0050. S2CID 233412239.
^ abcde"Leonard Goodwin - Telegraph". The Daily Telegraph. 14 January 2009. Retrieved 18 January 2009.
^"No. 47102". The London Gazette (Supplement). 30 December 1976. p. 3.
Leonard George Goodwin CMG FRS (11 July 1915 – 25 November 2008) was a British protozoologist noted for his work on testing the effectiveness of chemical...
including long-haired varieties and different colors. British zoologist LeonardGoodwin claimed most hamsters kept in the United Kingdom were descended from...
troops fighting in Sicily during the Second World War; research by LeonardGoodwin then showed pentostam was an effective treatment. The Institute for...
Hamster Council Journal. 57 (10): 1–4. Goodwin, Leonard; Wolstenholme, Gordon (16 July 1996), Dr LeonardGoodwin CMG FRS in interview with Sir Gordon Wolstenholme...
10 – Kevin Barrett, Australian rules footballer (d. 1984) July 11 – LeonardGoodwin, British protozoologist (d. 2008) July 12 Princess Catherine Ivanovna...
again call on Goodwin Procter lawyers to examine alleged corruption in the state's parole office. After World War II, partners Leonard Wheeler and Frank...
November – Richard Hickox, orchestral conductor (born 1948) 25 November LeonardGoodwin, pharmacologist (born 1915) Michael Lee, rock drummer (born 1969) Brian...
– Peter Lipton, American philosopher and academic (b. 1954) 2008 – LeonardGoodwin, British protozoologist (b. 1915) 2010 – Alfred Balk, American journalist...
director of Richard Rogers Partnership, President from 1999-2001 of RIBA, LeonardGoodwin CMG, Director from 1964-80 of the Nuffield Laboratories at the Institute...
Neva Goodwin Rockefeller (born June 1, 1944) is an American businesswoman. She's served as co-director of the Global Development And Environment Institute...
Mickey Goodwin dies of stroke - ESPN". Sports.espn.go.com. 2009-03-04. Retrieved 2013-12-03. Kimball, George (October 2008). Four Kings: Leonard, Hagler...
collector. William Gibson, 94, American playwright (The Miracle Worker). LeonardGoodwin, 93, British pharmacologist. Randy Gumpert, 90, American baseball player...
Goodwin was on a path toward becoming a professor of economics before leaving Nigeria. In season 3, it is revealed that Bob intends to make Goodwin his...
is based on his broken engagement to actress Ginnifer Goodwin. He began dating Ginnifer Goodwin in April 2009. The couple announced their engagement December...
1983 Ralph Lainson, FRS 1986 William Trager 1989 David F Clyde 1992 LeonardGoodwin 1995 Philip Edmund Clinton Manson-Bahr 1998 David Weatherall 2001 Brian...
organization founded in 1984 by Drs. John Henrik Clarke, Asa Grant Hilliard, Leonard Jeffries, Jacob H. Carruthers, Yosef Ben-Jochannan, and Maulana Karenga...
2006) Valerian Wellesley, 8th Duke of Wellington (d. 2014) 11 July – LeonardGoodwin, pharmacologist (died 2008) 15 July David Tree, actor (died 2009) Charlie...
while still performing in that production, he also played detective Archie Goodwin in what would have been television's first Nero Wolfe series, had it not...
"Leonard Betts" is the twelfth episode of the fourth season of the American science fiction television series The X-Files. It premiered on the Fox network...
dressed men in Britain in 2015. In 2017, Leech appeared alongside Ginnifer Goodwin in the Los Angeles stage production of Constellations. The play ran from...
Morrow starred in the critically acclaimed film Quiz Show (1994) as Dick Goodwin, a congressional investigator intent on uncovering the corruption behind...
Babcock. The film stars Gloria Jean, John Qualen, Bill Goodwin, Keefe Brasselle, Sheldon Leonard, Gus Schilling and Vince Barnett. The film was released...
suffered his first professional defeat when Leonard stopped him in the 14th round. In the 13th round, Leonard, behind on points on all 3 judges scorecards...
Joe Leonard Morgan (September 19, 1943 – October 11, 2020) was an American professional baseball second baseman who played 22 seasons in Major League...
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