dentate gyrus of hippocampal formation granule cell
subiculum
fossa
substantia nigra
trigeminal ganglion
condyle
primary motor cortex
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
DNA-binding transcription factor activity
Cellular component
Golgi apparatus
Biological process
anatomical structure morphogenesis
regulation of transcription, DNA-templated
Sources:Amigo / QuickGO
Orthologs
Species
Human
Mouse
Entrez
8216
66863
Ensembl
ENSG00000099949
ENSMUSG00000022761
UniProt
Q8N653
Q9CQ33
RefSeq (mRNA)
NM_006767
NM_025808 NM_001331226 NM_001331227
RefSeq (protein)
NP_006758
NP_001318155 NP_001318156 NP_080084
Location (UCSC)
Chr 22: 20.98 – 21 Mb
Chr 16: 17.33 – 17.34 Mb
PubMed search
[3]
[4]
Wikidata
View/Edit Human
View/Edit Mouse
Leucine Zipper Transcription Regulator Protein Structure
Leucine-zipper-like transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene.[5][6][7]
The LZTR1 gene provides instructions for making a protein among the class of the superfamily broad complex, tamtrack & brick-a-bac / poxvirus and zinc finger (BTB/POZ). The superfamily of proteins has a wide range of functions including chromatin condensation during conformation of the cell cycle. Other names associated with the LZTR gene are: BTBD29, LZTR-1, NS10, NS2, SWNTS2. This gene encodes a member of the BTB-kelch superfamily. Initially described as a putative transcriptional regulator based on weak homology to members of the basic leucine zipper-like family, the encoded protein subsequently has been shown to localize exclusively to the Golgi network where it may help stabilize the Golgi complex.[7]
^ abcGRCh38: Ensembl release 89: ENSG00000099949 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000022761 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Kurahashi H, Akagi K, Inazawa J, Ohta T, Niikawa N, Kayatani F, Sano T, Okada S, Nishisho I (Sep 1995). "Isolation and characterization of a novel gene deleted in DiGeorge syndrome". Hum Mol Genet. 4 (4): 541–9. doi:10.1093/hmg/4.4.541. PMID 7633402.
^Nacak TG, Leptien K, Fellner D, Augustin HG, Kroll J (Feb 2006). "The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis". J Biol Chem. 281 (8): 5065–71. doi:10.1074/jbc.M509073200. PMID 16356934.
transcriptional regulator 1 is a protein that in humans is encoded by the LZTR1 gene. The LZTR1 gene provides instructions for making a protein among the class...
Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A (1993). "LZTR1- and SMARCB1-Related Schwannomatosis". Schwannomatosis. University of Washington...
criteria was done by M.J. Smith in 2017. This included the consideration of a LZTR1 mutation (schwannomatosis) instead of NF2 and excluded bilateral vestibular...
spaceflight mission for the New Shepard RAF N.S. 10, a British NS class airship LZTR1, a protein and gene also called "NS10" Search for "ns10" or "ns-10" on...
Global Information
