Protein-coding gene in the species Homo sapiens
KCNQ2 Identifiers Aliases KCNQ2 , BFNC, BFNS1, EBN, EBN1, EIEE7, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1, potassium voltage-gated channel subfamily Q member 2, DEE7External IDs OMIM: 602235; MGI: 1309503; HomoloGene: 26174; GeneCards: KCNQ2; OMA:KCNQ2 - orthologs Gene location (Human) Chr. Chromosome 20 (human)[1] Band 20q13.33 Start 63,400,208 bp[1] End 63,472,677 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2 H4|2 103.57 cM Start 180,717,372 bp[2] End 180,777,093 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right hemisphere of cerebellum right frontal lobe right testis ganglionic eminence amygdala left testis nucleus accumbens dorsolateral prefrontal cortex superior frontal gyrus caudate nucleus
Top expressed in Region I of hippocampus proper CA3 field perirhinal cortex entorhinal cortex subiculum dentate gyrus primary visual cortex nucleus accumbens facial motor nucleus superior frontal gyrus
More reference expression data
BioGPS More reference expression data
Gene ontology Molecular function
ankyrin binding
ion channel activity
voltage-gated ion channel activity
voltage-gated potassium channel activity
potassium channel activity
calmodulin binding
protein binding
delayed rectifier potassium channel activity Cellular component
axon initial segment
node of Ranvier
membrane
integral component of membrane
integral component of plasma membrane
voltage-gated potassium channel complex
plasma membrane Biological process
regulation of ion transmembrane transport
ion transport
transmembrane transport
nervous system development
chemical synaptic transmission
potassium ion transport
potassium ion transmembrane transport Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl ENSG00000075043
UniProt RefSeq (mRNA) NM_004518 NM_001382235
NM_001003824 NM_001006675
RefSeq (protein) NP_004509 NP_001369164
NP_001003824 NP_001289817
Location (UCSC) Chr 20: 63.4 – 63.47 Mb Chr 2: 180.72 – 180.78 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Kv 7.2 (KvLQT2) is a voltage- and lipid-gated potassium channel protein coded for by the gene KCNQ2.
It is associated with benign familial neonatal epilepsy.
^ a b c ENSG00000281151 GRCh38: Ensembl release 89: ENSG00000075043, ENSG00000281151 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000016346 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine . 
Global Information
