Destructive fragmentation of the nucleus of a dying cell
Apoptosis
Karyorrhexis (from Greek κάρυον karyon 'kernel, seed, nucleus' and ῥῆξις rhexis 'bursting') is the destructive fragmentation of the nucleus of a dying cell[1] whereby its chromatin is distributed irregularly throughout the cytoplasm.[2] It is usually preceded by pyknosis and can occur as a result of either programmed cell death (apoptosis), cellular senescence, or necrosis.
In apoptosis, the cleavage of DNA is done by Ca2+ and Mg2+ -dependent endonucleases.
Morphological characteristics of pyknosis and other forms of nuclear destruction.
Microscopy of an apoptotic neutrophil with nuclear fragmentation (H&E stain)
^Zamzami N, Kroemer G (1999). "Apoptosis: Condensed matter in cell death". Nature. 401 (127): 127–8. Bibcode:1999Natur.401..127Z. doi:10.1038/43591. PMID 10490018. S2CID 36673000.
^Advances in Mutagenesis Research. Springer Science & Business Media. 2012. p. 11. ISBN 9783642781933. Retrieved 11 November 2017.
Karyorrhexis (from Greek κάρυον karyon 'kernel, seed, nucleus' and ῥῆξις rhexis 'bursting') is the destructive fragmentation of the nucleus of a dying...
is usually associated with karyorrhexis and occurs mainly as a result of necrosis, while in apoptosis after karyorrhexis the nucleus usually dissolves...
nucleus of a cell undergoing necrosis or apoptosis. It is followed by karyorrhexis, or fragmentation of the nucleus. Pyknosis (from Ancient Greek πυκνός...
cellular changes of necrosis, the nucleus breaks into fragments (known as karyorrhexis). The nucleus changes in necrosis and characteristics of this change...
ballooned cells have (small) pyknotic nuclei or nuclei that are undergoing karyorrhexis, i.e. in the process of disintegrating. The cytoplasm of cells undergoing...
(pyknosis, karyorrhexis) 1–3 days (loss of nuclei) Depends on size of infarction Neutrophil infiltration 12–24 h 1–3 days 5–7 days Karyorrhexis of neutrophils...
discontinuous and the DNA inside it is fragmented in a process referred to as karyorrhexis. The nucleus breaks into several discrete chromatin bodies or nucleosomal...
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Morphological characteristics of pyknosis and other forms of nuclear destruction.
Microscopy of an apoptotic neutrophil with nuclear fragmentation (H&E stain)
