Karen Joy Shaw is an American microbiologist and discoverer of novel antifungal and antibacterial compounds. She is best known for her work on aminoglycoside resistance in bacteria[1] as well as leading drug discovery research teams. As Senior Vice President of Biology at Trius Therapeutics, Inc.[2] her work was critical to the development of the oxazolidinone antibiotic tedizolid phosphate (Sivextro) as well as the discovery of the TriBE inhibitors,[3] a novel class of DNA gyrase/Topoisomerase IV antibacterial agents that target both Gram-positive and Gram-negative organisms.[2] As Chief Scientific Officer at Amplyx Pharmaceuticals,[4] Shaw was responsible for the preclinical development of the novel antifungal fosmanogepix, a first-in-class broad-spectrum antifungal prodrug that is currently in Phase 2 clinical development for the treatment of invasive fungal infections.[5] She also discovered APX2039, a unique Gwt1 inhibitor[6] that is in preclinical development for the treatment of cryptococcal meningitis.[7]
^Shaw, K. J.; Rather, P. N.; Hare, R. S.; Miller, G. H. (1993). "Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes". Microbiological Reviews. 57 (1): 138–163. doi:10.1128/MR.57.1.138-163.1993. ISSN 0146-0749. PMC 372903. PMID 8385262.
^manager, Community. "Karen J. Shaw". REVIVE. Retrieved 2020-12-01.
KarenJoyShaw is an American microbiologist and discoverer of novel antifungal and antibacterial compounds. She is best known for her work on aminoglycoside...
on a class of drugs used to treat symptoms of adult-onset diabetes KarenJoyShaw (B.S. 1976), American microbiologist and discoverer of novel antifungal...
Rachel Frances Shaw (born 1981) is an American actress, writer and director. She is best known for playing Bridgette Bird on the Showtime series SMILF...
Joy Osmanski (born October 29, 1975) is an American actress. She is best known for her wide range of comedic roles on the TV shows The Loop, Samantha...
Joy Harjo (/ˈhɑːrdʒoʊ/ HAR-joh; born May 9, 1951) is an American poet, musician, playwright, and author. She served as the 23rd United States Poet Laureate...
Jennifer Brantley Cait Brennan Camille Bright-Smith Logan Brill Lane Brody Karen Brooks Alison Brown Bonnie Brown Lacey Brown Maxine Brown Shannon Brown...
Cultural Studies of the Modern Middle Ages. Eileen A. Joy, ed. New York: Palgrave Macmillan, 2007. Shaw, Simon; Peavy, Linda; and Smith, Ursula. Frontier...
trying to impress Joy so she can have a weekend out. Joy allows Natalie to leave for the weekend with prison officer Kevin Spiers. Joy changes all the cells...
wedding, which Honeybee's family, the Shaws, overhear; the Tobins are forced to reveal their family secret to the Shaws, who reassure them that no family...
Elbernita "Twinkie" Clark (born 1954), Dorinda Clark-Cole (born 1957), and Karen Clark Sheard (born 1960). The Clark Sisters are the daughters of gospel...
Selby as Julie Corrigan Jamie Lehane as Jacko Morgan Ian Steele as Brian Shaw Alice Dawnay as Alice Rowe Nina Fry as Robyn Stone John Pickard as Neil Timpson...
Movie". ComingSoon. Retrieved May 14, 2024. O'Rourke, Ryan (May 21, 2024). "Karen Gillan Finds an Unlikely Friend in First 'Late Bloomers' Trailer [Exclusive]"...
awkward and has limited knowledge about pop culture. Her birth name was Joy Keenan, while her brother's birth name was Kyle Keenan; their names were...
Retrieved September 4, 2022. Strauss, Matthew (July 18, 2022). "Caroline Shaw and Attacca Quartet Announce New Album, Share Song". Pitchfork. Retrieved...
in the Los Angeles area. She also lived for a brief period with actress Karen Black, who was a mentor to her. Lewis dropped out of high school at age...
suicidaire consentant) — Jeanne-Marie Poulain, Line Sander Egede Infinity Pool — Karen Harnisch, Andrew Cividino, Christina Piovesan, Noah Segal, Rob Cotterill...
Year Title Role Notes 2013 Law & Order: Special Victims Unit Gabby Shaw episode: "Traumatic Wound" 2014 The Leftovers Hailey episode: "Pilot" 2014–2018...