Not to be confused with Kaolin cephalin clotting time.
Kaolin clotting time
Test of
Blood plasma[1]
Kaolin clotting time (KCT) is a sensitive test to detect lupus anticoagulants.[2] There is evidence that suggests it is the most sensitive test for detecting lupus anticoagulants.[3] It can also detect factor VIII inhibitors but is sensitive to unfractionated heparin as well.[4]
The KCT on whole blood is known as the "Activated Clotting Time" (ACT) and is widely used in various instruments during surgery such as cardiac bypass to monitor heparin.[5]
^Gronowski, Ann M. (2004). Handbook of Clinical Laboratory Testing During Pregnancy. Springer Science & Business Media. p. 308. ISBN 9781592597871.
^Radhakrishnan, Kottayam (2013). "Kaolin Clotting Time". Haemostasis. Methods in Molecular Biology. Vol. 992. pp. 335–339. doi:10.1007/978-1-62703-339-8_25. ISBN 978-1-62703-338-1. PMID 23546725.
^Exner, T; Triplett, D. A.; Taberner, D. A.; Howard, M. A.; Harris, E. N. (1990). "Comparison of test methods for the lupus anticoagulant: International survey on lupus anticoagulants-I (ISLA-1)". Thrombosis and Haemostasis. 64 (3): 478–84. doi:10.1055/s-0038-1647340. PMID 2128977. S2CID 32243774.
^"Kaolin Clotting Time [KCT]". Archived from the original on 26 November 2014. Retrieved 26 November 2014.
^De Vries, A.J.; Lansink-Hartgring, A,O.; Fernhout, F.J.; Huet,R,C,G.; van den Heuvel, E,R. (2017) "The activated clotting time in cardiac surgery: should celite or kaolin be used?" Interact Cardiovascular and Thoracic Surgery. 24 (4): 549-554
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Kaolinclottingtime (KCT) is a sensitive test to detect lupus anticoagulants. There is evidence that suggests it is the most sensitive test for detecting...
blood. A historical name for this measure is the kaolin-cephalin clottingtime (KCCT), reflecting kaolin and cephalin as materials historically used in...
that do not pre-warm the vial or sample may see increased time to clotting because clotting times increase with temperature. A common reference range...
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Thrombosis and Haemostasis no longer recommends the kaolinclottingtime, dilute thromboplastin time, and Taipan/Ecarin snake venom based assays due to...
which promoted blood clotting. The zeolite would have an exothermic (heat-releasing) reaction with blood during the clotting process, which could cause...
Phospholipid-sensitive functional clotting testing, such as the dilute Russell's viper venom time, or the Kaolinclottingtime. As a further confirmation, a...
of QuikClot uses a nonwoven material impregnated with kaolin, an inorganic mineral activating Factor XII, in turn accelerating natural clotting. Unlike...
bleeding. Their use is well established in many military and trauma units. Kaolin (and the zeolite in it) activate the coagulation cascade, and have been...
There are several types of assays that can be run using TEG: Standard (kaolin), RapidTEG, heparinase, Functional Fibrinogen and PlateletMapping. A standard...
37-year-old railroad brakeman John Hageman (1918) was found to have prolonged clottingtime in test tubes, even though he had no hemorrhagic symptoms. Hageman was...
placebo regarding buccal mucosal bleeding time, prothrombin time, activated partial thromboplastin time, and clotting parameters in canines. There was no high-quality...
powder are larger than those in loose powder and can give off a thick, clotted appearance when overused. Pressed powder can also be used for setting makeup...
companies in Cornwall include Imerys who are major producers of kaolin. Rodda's make clotted cream near Scorrier, off the A30 east of Redruth. Fugro Seacore...
dairying, leading to the production of Cornwall's other famous export, clotted cream. Though it has declined significantly agriculture is still of economic...
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