Sanjay Gandhi Postgraduate Institute of Medical Sciences
Academic work
Institutions
National Institute of Health
Johns Hopkins University School of Medicine
Children's National Medical Center
George Washington University School of Medicine Binghamton University
Kanneboyina Nagaraju is the Dean of the School of Pharmacy and Pharmaceutical Sciences at the State University of New York (SUNY), Binghamton. He holds the prestigious title of SUNY Distinguished Professor, the highest faculty rank awarded by the State University of New York system.
Nagaraju is a renowned medical scientist and immunologist, known for developing the MHC Class I transgenic mouse model for autoimmune myositis.[1] He played a pivotal role in the identification and development of Vamorolone (AGAMREE), a potent anti-inflammatory and membrane-stabilizing dissociated glucocorticoid with fewer side effects, in collaboration with Eric Hoffman and John McCall. Vamorolone has been approved by the Food and Drug Administration, the European Medicines Agency, and the Medicines and Healthcare Products Regulatory Agency for the treatment of children with Duchenne Muscular Dystrophy. Additionally, Nagaraju has led global initiatives to improve the rigor and reproducibility of preclinical drug trials and phenotyping in neuromuscular disease models.[2][3][4]
^Nagaraju, K.; Raben, N.; Loeffler, L.; Parker, T.; Rochon, P. J.; Lee, E.; Danning, C.; Wada, R.; Thompson, C. (1 August 2000). "Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies". Proceedings of the National Academy of Sciences of the United States of America. 97 (16): 9209–9214. doi:10.1073/pnas.97.16.9209. ISSN 0027-8424. PMC 16847. PMID 10922072.
^Willmann, Raffaella; Luca, Annamaria De; Nagaraju, Kanneboyina; Rüegg, Markus A. (14 May 2015). "Best Practices and Standard Protocols as a Tool to Enhance Translation for Neuromuscular Disorders" (PDF). Journal of Neuromuscular Diseases. 2 (2): 113–117. doi:10.3233/jnd-140067. ISSN 2214-3599. PMID 27858730.
^Gordish-Dressman, Heather; Willmann, Raffaella; Dalle Pazze, Laura; Kreibich, Arati; van Putten, Maaike; Heydemann, Ahlke; Bogdanik, Laurent; Lutz, Cathleen; Davies, Kay (2018). ""Of Mice and Measures": A Project to Improve How We Advance Duchenne Muscular Dystrophy Therapies to the Clinic". Journal of Neuromuscular Diseases. 5 (4): 407–417. doi:10.3233/JND-180324. ISSN 2214-3599. PMC 6218134. PMID 30198876.
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KanneboyinaNagaraju is the Dean of the School of Pharmacy and Pharmaceutical Sciences at the State University of New York (SUNY), Binghamton. He holds...
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