Protein-coding gene in the species Homo sapiens
KDM7A Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3KV5, 3KV6, 3KV9, 3KVA, 3KVB, 3U78
Identifiers Aliases KDM7A , JHDM1D, lysine demethylase 7AExternal IDs MGI: 2443388; HomoloGene: 25281; GeneCards: KDM7A; OMA:KDM7A - orthologs Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q34 Start 140,084,746 bp[1] End 140,176,983 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B1 Start 39,113,557 bp[2] End 39,183,723 bp[2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow monocyte bone marrow cells jejunal mucosa trabecular bone gastrocnemius muscle blood sperm pericardium thymus
Top expressed in blood secondary oocyte left lung lobe cerebellar vermis trigeminal ganglion soleus muscle body of femur intercostal muscle olfactory tubercle triceps brachii muscle
More reference expression data
BioGPS
Gene ontology Molecular function
2-oxoglutarate-dependent dioxygenase activity
iron ion binding
histone H3-methyl-lysine-9 demethylase activity
histone H4-methyl-lysine-20 demethylase activity
dioxygenase activity
metal ion binding
methylated histone binding
histone H3-methyl-lysine-36 demethylase activity
oxidoreductase activity
histone H3-tri/di-methyl-lysine-27 demethylase activity
histone demethylase activity
zinc ion binding
Cellular component
nucleoplasm
nucleolus
nucleus
Biological process
regulation of transcription, DNA-templated
histone H3-K27 demethylation
histone H3-K9 demethylation
histone H4-K20 demethylation
transcription, DNA-templated
nervous system development
positive regulation of transcription, DNA-templated
histone H3-K36 demethylation
midbrain development
chromatin organization
Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez Ensembl UniProt RefSeq (mRNA) RefSeq (protein) Location (UCSC) Chr 7: 140.08 – 140.18 Mb Chr 6: 39.11 – 39.18 Mb PubMed search [3] [4]
Wikidata View/Edit Human View/Edit Mouse
Lysine demethylase 7A is a protein that in humans is encoded by the KDM7A gene.
[5]
^ a b c GRCh38: Ensembl release 89: ENSG00000006459 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042599 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Entrez Gene: Lysine demethylase 7A". Retrieved 2016-04-09 .