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Julie Overbaugh information


Julie Overbaugh
Born
Pennsylvania, USA
Academic background
EducationBS, chemistry, 1979, University of Connecticut
Ph.D., Biochemistry, 1983, University of Colorado Boulder
ThesisMicrobial glutathoine peroxidases and transferases (1983)
Academic work
InstitutionsFred Hutchinson Cancer Research Center
University of Washington
Harvard

Julie M. Overbaugh is an American virologist. She is a professor at the Fred Hutchinson Cancer Research Center. Overbaugh is best known for her translational approach to studying HIV transmission and pathogenesis and studies of how the antibody response evolves to recognize viruses. Her work in maternal and infant HIV transmission helped make clear the risk posed by breastfeeding and highlighted unique characteristics of an infant immune response that could inform vaccine development. Major scientific contributions to the understanding of HIV transmission and pathogenesis also include: identifying a bottleneck that selects one or a few variants during HIV transmission; demonstrating the importance of female hormones in HIV infection risk; showing the HIV reinfection is common; demonstrating a role for antibodies that mediate ADCC in clinical disease; showing that HIV infected infants develop unique neutralizing antibody responses to HIV.

Overbaugh is an elected member of the National Academy of Sciences and the American Academy of Arts and Sciences. In addition to being recognized for her scientific contributions, she is also recognized for her mentoring, her advocacy for equity and her commitment to global health.

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68.4.2458-2467.1994. PMC 236723. PMID 8139030. Rohn, Jennifer L.; Overbaugh, Julie (January 1995). "In vivo selection of long terminal repeat alterations...

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