Isaria cicadae information

Isaria cicadae
Scientific classification
Domain:	Eukaryota
Kingdom:	Fungi
Division:	Ascomycota
Class:	Sordariomycetes
Order:	Hypocreales
Family:	Cordycipitaceae
Genus:	Isaria
Species:	I. cicadae
Binomial name
	Isaria cicadae; Isaria cicadae Miq., Bull. Sci. phys. nat. Néerl.: 85 (1838)
	This range map depicts global occurrences of Isaria cicadae and synonymous species including Cordyceps cicadae Shing and Massee, and Paecilomyces cicadae.
Synonyms
	Cordyceps cicadae (Miq.) Massee 1895; Cordyceps cicadae S.Z. Shing 1975; Paecilomyces cicadae (Miq.) Samson (1974);

Isaria cicadae is an ascomycete fungus that parasitizes cicada larvae.^[1] It forms white and yellow asexual fruiting structures resembling synnema.^[2] While mostly being found throughout Asia in warm, humid regions, it has been found on various other continents.^[3] It is known in Traditional Chinese Medicine as Chan Hua and commonly called “cicada flower.”^[4] Its medicinal uses date back to the fifth century AD in China.^[5] It can also be used in various foods and tonics.^[6]

^ Nxumalo, Winston; Elateeq, Ahmed Abdelfattah; Sun, Yanfang (2020). "Can Cordyceps cicadae be used as an alternative to Cordyceps militaris and Cordyceps sinensis? – A review". Journal of Ethnopharmacology. 257: 112879. doi:10.1016/j.jep.2020.112879. PMID 32305637. S2CID 216029199.
^ Lu, Yuzhen; Luo, Feifei; Cen, Kai; Xiao, Guohua; Yin, Ying; Li, Chunru; Li, Zengzhi; Zhan, Shuai; Zhang, Huizhan; Wang, Chengshu (2017). "Omics data reveal the unusual asexual-fruiting nature and secondary metabolic potentials of the medicinal fungus Cordyceps cicadae". BMC Genomics. 18 (1): 668. doi:10.1186/s12864-017-4060-4. ISSN 1471-2164. PMC 5577849. PMID 28854898.
^ WEN, TING-CHI; XIAO, YUAN-PIN; HAN, YAN-FENG; HUANG, SHI-KE; ZHA, LING-SHENG; HYDE, KEVIN D.; KANG, JI-CHUAN (2017-03-28). "Multigene phylogeny and morphology reveal that the Chinese medicinal mushroom 'Cordyceps gunnii' is Metacordyceps neogunnii sp. nov". Phytotaxa. 302 (1): 27. doi:10.11646/phytotaxa.302.1.2. ISSN 1179-3163. S2CID 90870374.
^ Chunyu, Yan-Jie; Lu, Zhen-Ming; Luo, Zhi-Shan; Li, Shuo-Shuo; Li, Hui; Geng, Yan; Xu, Hong-Yu; Xu, Zheng-Hong; Shi, Jin-Song (2019-07-12). "Promotion of Metabolite Synthesis in Isaria cicadae, a Dominant Species in the Cicada Flower Microbiota, by Cicada Pupae". Journal of Agricultural and Food Chemistry. 67 (31): 8476–8484. doi:10.1021/acs.jafc.9b02705. ISSN 0021-8561. PMID 31298527. S2CID 199635881.
^ Li, I-Chen; Lin, Shan; Tsai, Yueh-Ting; Hsu, Jui-Hsia; Chen, Yen-Lien; Lin, Wen-Hsin; Chen, Chin-Chu (2018-08-13). "Cordyceps cicadae mycelia and its active compound HEA exert beneficial effects on blood glucose in type 2 diabetic db/db mice". Journal of the Science of Food and Agriculture. 99 (2): 606–612. doi:10.1002/jsfa.9221. ISSN 0022-5142. PMID 29952113. S2CID 49484322.
^ Tian, Juanjuan; Zhang, Cangping; Wang, Xiaomeng; Rui, Xin; Zhang, Qiuqin; Chen, Xiaohong; Dong, Mingsheng; Li, Wei (2021). "Structural characterization and immunomodulatory activity of intracellular polysaccharide from the mycelium of Paecilomyces cicadae TJJ1213". Food Research International. 147: 110515. doi:10.1016/j.foodres.2021.110515. PMID 34399493.

[:0-1] Nxumalo, Winston; Elateeq, Ahmed Abdelfattah; Sun, Yanfang (2020). "Can Cordyceps cicadae be used as an alternative to Cordyceps militaris and Cordyceps sinensis? – A review". Journal of Ethnopharmacology. 257: 112879. doi:10.1016/j.jep.2020.112879. PMID 32305637. S2CID 216029199.

[:1-2] Lu, Yuzhen; Luo, Feifei; Cen, Kai; Xiao, Guohua; Yin, Ying; Li, Chunru; Li, Zengzhi; Zhan, Shuai; Zhang, Huizhan; Wang, Chengshu (2017). "Omics data reveal the unusual asexual-fruiting nature and secondary metabolic potentials of the medicinal fungus Cordyceps cicadae". BMC Genomics. 18 (1): 668. doi:10.1186/s12864-017-4060-4. ISSN 1471-2164. PMC 5577849. PMID 28854898.

[:2-3] WEN, TING-CHI; XIAO, YUAN-PIN; HAN, YAN-FENG; HUANG, SHI-KE; ZHA, LING-SHENG; HYDE, KEVIN D.; KANG, JI-CHUAN (2017-03-28). "Multigene phylogeny and morphology reveal that the Chinese medicinal mushroom 'Cordyceps gunnii' is Metacordyceps neogunnii sp. nov". Phytotaxa. 302 (1): 27. doi:10.11646/phytotaxa.302.1.2. ISSN 1179-3163. S2CID 90870374.

[4] Chunyu, Yan-Jie; Lu, Zhen-Ming; Luo, Zhi-Shan; Li, Shuo-Shuo; Li, Hui; Geng, Yan; Xu, Hong-Yu; Xu, Zheng-Hong; Shi, Jin-Song (2019-07-12). "Promotion of Metabolite Synthesis in Isaria cicadae, a Dominant Species in the Cicada Flower Microbiota, by Cicada Pupae". Journal of Agricultural and Food Chemistry. 67 (31): 8476–8484. doi:10.1021/acs.jafc.9b02705. ISSN 0021-8561. PMID 31298527. S2CID 199635881.

[:4-5] Li, I-Chen; Lin, Shan; Tsai, Yueh-Ting; Hsu, Jui-Hsia; Chen, Yen-Lien; Lin, Wen-Hsin; Chen, Chin-Chu (2018-08-13). "Cordyceps cicadae mycelia and its active compound HEA exert beneficial effects on blood glucose in type 2 diabetic db/db mice". Journal of the Science of Food and Agriculture. 99 (2): 606–612. doi:10.1002/jsfa.9221. ISSN 0022-5142. PMID 29952113. S2CID 49484322.

[6] Tian, Juanjuan; Zhang, Cangping; Wang, Xiaomeng; Rui, Xin; Zhang, Qiuqin; Chen, Xiaohong; Dong, Mingsheng; Li, Wei (2021). "Structural characterization and immunomodulatory activity of intracellular polysaccharide from the mycelium of Paecilomyces cicadae TJJ1213". Food Research International. 147: 110515. doi:10.1016/j.foodres.2021.110515. PMID 34399493.