INAVA information

INAVA
Identifiers
Aliases	INAVA, chromosome 1 open reading frame 106, C1orf106, innate immunity activator
External IDs	OMIM: 618051 MGI: 1921579 HomoloGene: 10103 GeneCards: INAVA
Gene location (Human)
Chr.	Chromosome 1 (human)
End	200,915,742 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	136,162,002 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; palpebral conjunctiva; ; pancreatic ductal cell; ; duodenum; ; bronchial epithelial cell; ; nipple; ; skin of abdomen; ; rectum; ; human penis; ; vulva;
	Top expressed in
	epithelium of stomach; ; left colon; ; lip; ; ileum; ; duodenum; ; spermatid; ; yolk sac; ; proximal tubule; ; stria vascularis; ; esophagus;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding;
Cellular component	nucleus; cytoplasm;
Biological process	pattern recognition receptor signaling pathway; cytokine production involved in immune response; response to peptidoglycan; response to muramyl dipeptide; positive regulation of interleukin-1 beta production; positive regulation of interleukin-10 production; positive regulation of interleukin-6 production; positive regulation of stress-activated MAPK cascade; positive regulation of I-kappaB kinase/NF-kappaB signaling; nucleotide-binding oligomerization domain containing 2 signaling pathway; reactive oxygen species biosynthetic process; immune system process; innate immune response; positive regulation of protein ubiquitination; adherens junction maintenance; intestinal epithelial structure maintenance;
	Sources:Amigo / QuickGO
Orthologs
	55765
	67313
	ENSG00000163362
	ENSMUSG00000041605
	Q3KP66
	Q7TN12
	NM_001142569; NM_018265; NM_001367289; NM_001367290
	NM_028872
	NP_001136041; NP_060735; NP_001354218; NP_001354219
	NP_083148; NP_001392081; NP_001392082; NP_001392083
	Wikidata
View/Edit Human	View/Edit Mouse

INAVA, sometimes referred to as hypothetical protein LOC55765, is a protein of unknown function that in humans is encoded by the INAVA gene.^[5] Less common gene aliases include FLJ10901 and MGC125608.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000163362 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000041605 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "NCBI Gene 55765". Retrieved 10 February 2014.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000163362 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000041605 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[NCBI-5] "NCBI Gene 55765". Retrieved 10 February 2014.