DNA-binding protein Ikaros also known as Ikaros family zinc finger protein 1 is a protein that in humans is encoded by the IKZF1 gene.[5][6][7]
^ abcGRCh38: Ensembl release 89: ENSG00000185811 – Ensembl, May 2017
^ abcGRCm38: Ensembl release 89: ENSMUSG00000018654 – Ensembl, May 2017
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Georgopoulos K, Moore DD, Derfler B (October 1992). "Ikaros, an early lymphoid-specific transcription factor and a putative mediator for T cell commitment". Science. 258 (5083): 808–12. Bibcode:1992Sci...258..808G. doi:10.1126/science.1439790. PMID 1439790.
^Hahm K, Ernst P, Lo K, Kim GS, Turck C, Smale ST (November 1994). "The lymphoid transcription factor LyF-1 is encoded by specific, alternatively spliced mRNAs derived from the Ikaros gene". Molecular and Cellular Biology. 14 (11): 7111–23. doi:10.1128/mcb.14.11.7111. PMC 359245. PMID 7935426.
^"Entrez Gene: IKZF1 IKAROS family zinc finger 1 (Ikaros)".
family zinc finger protein 1 is a protein that in humans is encoded by the IKZF1 gene. Ikaros is a transcription factor that is encoded by the IKZF genes...
in the rapid degradation of several disease-related proteins including IKZF1, IKZF3, and CSNK1A1. Lenalidomide was approved for medical use in the United...
Common inherited risk factors include mutations in ARID5B, CDKN2A/2B, CEBPE, IKZF1, GATA3, PIP4K2A and, more rarely, TP53. These genes play important roles...
Heaven's Lost Property Ikaros, a transcription factor encoded by the human IKZF1 gene Icarus (disambiguation) This disambiguation page lists articles associated...
S, Uckun FM (December 2013). "Incidence and biological significance of IKZF1/Ikaros gene deletions in pediatric Philadelphia chromosome negative and...
This family of transcription factors consists of five members: Ikaros (Ikzf1), Helios (Ikzf2), Aiolos (Ikzf3), Eos (Ikzf4), and Pegasus (Ikzf5). The...
disease. In patients with alopecia, one of the genes that are hyperactive is IKZF1, which results in overproduction of immune cells that subsequently attack...
development.[supplied by OMIM] IKZF4 has been shown to interact with CTBP1 and IKZF1. GRCh38: Ensembl release 89: ENSG00000123411 – Ensembl, May 2017 GRCm38:...
include (but are not limited to) EGR1, p53, E2F3, E2F4, PLAG1, NeuroD2, Myf5, IKZF1, SMAD3, KRAB, MZF1, and c-Myb. Expression of QSER1 is seen at levels lower...
C17orf78-NUTM1 (C17orf78 is also termed ATAD5), CHD4-NUTM1, RUNX1-NUTM1, IKZF1-NUTM1, and SLC12A6-NUTM1 fusion genes. Individuals with these NUTM1 fusion...
reports show that IMiDs bind to CRL4CRBN and promote the degradation of IKZF1 and IKZF3 transcription factors, which are not normally targeted by CRL4...
with HDAC1, Zinc finger and BTB domain-containing protein 16, SUDS3 and IKZF1. Transcription coregulator GRCh38: Ensembl release 89: ENSG00000127511 –...
of: Cdt1 p21 PR-Set7/SET8 p12 subunit of DNA polymerase δ SAMHD1† UNG2† IKZF1§ IKZF3§ †protein is a CRL4 substrate only when directed by viral proteins...
developing eye. The expression of Osr1 is negatively regulated by Runx2 and Ikzf1. These genes are involved in osteoblast and lymphocyte differentiation through...
Table 6. List of proteins that interact with FAM214B Protein Description IKZF1 DNA-binding protein Ikaros TRIM27 Zinc finger protein RFP FHL5 Four and...
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