IFRD1 information

IFRD1
Identifiers
Aliases	IFRD1, PC4, TIS7, interferon related developmental regulator 1
External IDs	OMIM: 603502; MGI: 1316717; HomoloGene: 31043; GeneCards: IFRD1; OMA:IFRD1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	112,481,017 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	40,298,503 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; jejunal mucosa; ; Skeletal muscle tissue of rectus abdominis; ; Epithelium of choroid plexus; ; germinal epithelium; ; vena cava; ; amniotic fluid; ; gastric mucosa; ; saphenous vein; ; right lung;
	Top expressed in
	secondary oocyte; ; granulocyte; ; zygote; ; parotid gland; ; muscle of thigh; ; lip; ; ventricular zone; ; superior cervical ganglion; ; intercostal muscle; ; cumulus cell;
	More reference expression data
	More reference expression data
Orthologs
	3475
	15982
	ENSG00000006652
	ENSMUSG00000001627
	O00458
	P19182
	NM_001007245; NM_001197079; NM_001197080; NM_001550
	NM_013562
	NP_001007246; NP_001184008; NP_001184009; NP_001541
	NP_038590
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon-related developmental regulator 1 is a protein that in humans is encoded by the IFRD1 gene.^[5]^[6] The gene is expressed mostly in neutrophils, skeletal and cardiac muscle, the brain, and the pancreas.^[5]^[6] The rat and the mouse homolog genes of interferon-related developmental regulator 1 gene (and their proteins) are also known with the name PC4 ^[7] and Tis21, respectively. IFRD1 is member of a gene family that comprises a second gene, IFRD2, also known as SKmc15.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000006652 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000001627 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b ^c Buanne P, Incerti B, Guardavaccaro D, Avvantaggiato V, Simeone A, Tirone F (Nov 1998). "Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes". Genomics. 51 (2): 233–42. doi:10.1006/geno.1998.5260. PMID 9722946.
^ ^a ^b ^c "Entrez Gene: IFRD1 interferon-related developmental regulator 1".
^ Tirone F, Shooter EM (March 1989). "Early gene regulation by nerve growth factor in PC12 cells: induction of an interferon-related gene". Proc. Natl. Acad. Sci. U.S.A. 86 (6): 2088–92. Bibcode:1989PNAS...86.2088T. doi:10.1073/pnas.86.6.2088. PMC 286853. PMID 2467301.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000006652 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000001627 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9722946-5] Buanne P, Incerti B, Guardavaccaro D, Avvantaggiato V, Simeone A, Tirone F (Nov 1998). "Cloning of the human interferon-related developmental regulator (IFRD1) gene coding for the PC4 protein, a member of a novel family of developmentally regulated genes". Genomics. 51 (2): 233–42. doi:10.1006/geno.1998.5260. PMID 9722946.

[entrez-6] "Entrez Gene: IFRD1 interferon-related developmental regulator 1".

[pmid2467301-7] Tirone F, Shooter EM (March 1989). "Early gene regulation by nerve growth factor in PC12 cells: induction of an interferon-related gene". Proc. Natl. Acad. Sci. U.S.A. 86 (6): 2088–92. Bibcode:1989PNAS...86.2088T. doi:10.1073/pnas.86.6.2088. PMC 286853. PMID 2467301.

IFRD1 information

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