Top view of the hslV/hslU complex isolated from E. coli (PDB ID 1G4A).
Identifiers
EC no.
3.4.25.2
Databases
IntEnz
IntEnz view
BRENDA
BRENDA entry
ExPASy
NiceZyme view
KEGG
KEGG entry
MetaCyc
metabolic pathway
PRIAM
profile
PDB structures
RCSB PDB PDBe PDBsum
Search
PMC
articles
PubMed
articles
NCBI
proteins
Heat shock protein HslU
Identifiers
Symbol
HslU
InterPro
IPR004491
ATP-dependent protease, HslV subunit
Identifiers
Symbol
HslV
InterPro
IPR022281
The heat shock proteins HslV and HslU (HslVU complex; also known as ClpQ and ClpY respectively, or ClpQY) are expressed in many bacteria such as E. coli in response to cell stress.[1] The hslV protein is a protease and the hslU protein is an ATPase; the two form a symmetric assembly of four stacked rings, consisting of an hslV dodecamer bound to an hslU hexamer, with a central pore in which the protease and ATPase active sites reside. The hslV protein degrades unneeded or damaged proteins only when in complex with the hslU protein in the ATP-bound state. HslV is thought to resemble the hypothetical ancestor of the proteasome, a large protein complex specialized for regulated degradation of unneeded proteins in eukaryotes, many archaea, and a few bacteria. HslV bears high similarity to core subunits of proteasomes.[2]
^Ramachandran R, Hartmann C, Song HK, Huber R, Bochtler M. (2002). Functional interactions of HslV (ClpQ) with the ATPase HslU (ClpY). Proc Natl Acad Sci USA 99(11):7396-401.
^Gille C, Goedel A, Schloetelburg C, Preißner R, Kloetzell PM, Gobel UB, Frommell C. (2003). A Comprehensive View on Proteasomal Sequences: Implications for the Evolution of the Proteasome. J Mol Biol 326: 1437–1448.
The heat shock proteins HslV and HslU (HslVU complex; also known as ClpQ and ClpY respectively, or ClpQY) are expressed in many bacteria such as E. coli...
HSLuv or HslUV may refer to: HslVU, a protein HslUV protease, an enzyme HSLuv, a colorspace This disambiguation page lists articles associated with the...
present in humans as mitochondrial enzymes. ClpYQ is another name for the HslVU complex, a heat shock protein complex thought to resemble the hypothetical...
30. Harris 1985, p. 33. Harris 1985, p. 32. Harris 1985, p. 34. "La tour a vu le jour à Levallois". Le Parisien (in French). April 30, 2004. Archived from...
destinations located to the north and east of the country. The station is also on HSL-Zuid, a dedicated high-speed line designed for long distance and international...
ISSN 2325-1042. Whyte, Kyle Powys (November 10, 2016), "Is it colonial déjà vu? Indigenous peoples and climate injustice", Humanities for the Environment...
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Archived from the original (PDF) on October 31, 2008. Retrieved August 2, 2010. Vu, Michelle A (July 29, 2008). "Rick Warren: Pastors Shouldn't Endorse Politicians"...
Archived from the original on January 5, 2008. Retrieved February 8, 2008. "VuQube mobile satellite TV for truck and RV users". DieselBoss. Archived from...
1Full member Young Croatian Liberals Mladi hrvatski liberali, MHL Croatia HSLS Youth 1Full member Croatian People's Party Youth Mladi Hrvatske Narodne Stranke...
NAS Quonset Point, RI VRF-31 COMP 291 (1981–1987) Aircraft Ferry Squadron HSL-74 (1985–1994) "The Demon Elves", formerly HS-74 VR-62 (1994–1996) "The Nor'...
attracted many politicians from other parties, notably from the Volksunie (VU) and the Christian People's Party (CVP). However, despite the fact that many...
312. ISBN 9783540740773. Landau, Susan (2015), "NSA and Dual EC_DRBG: Déjà Vu All Over Again?", The Mathematical Intelligencer, 37 (4): 72–83, doi:10...
evolution of the All-Volunteer Force (2006) Hirschman, Charles; Preston, Samuel; Vu, Manh Loi (December 1995). "Vietnamese Casualties During the American War:...
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