Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Yverify (what is YN ?)
Infobox references
Chemical compound
Horsfiline is an oxindole alkaloid found in the plant Horsfieldia superba,[1] which is used in traditional herbal medicine. It has analgesic effects[medical citation needed] and has been the subject of research both to produce it synthetically by convenient routes[2][3][4][5][6][7][8] and to develop analogues and derivatives which may have improved analgesic effects.[9][10]
It is a member of the spiroindolone class. Elacomine has a similar chemical structure.
^Jossang A, Jossang P, Hadi HA, Sevenet T, Bodo B (1991). "An oxindole alkaloid from Horsfieldia superba". Journal of Organic Chemistry. 56 (23): 6527–6530. doi:10.1021/jo00023a016.
^Lakshmaiah G, Kawabata T, Shang M, Fuji K (March 1999). "Total Synthesis of (-)-Horsfiline via Asymmetric Nitroolefination". The Journal of Organic Chemistry. 64 (5): 1699–1704. doi:10.1021/jo981577q. PMID 11674239.
^Cravotto G, Giovenzana GB, Pilati T, Sisti M, Palmisano G (December 2001). "Azomethine ylide cycloaddition/reductive heterocyclization approach to oxindole alkaloids: asymmetric synthesis of (-)-horsfiline". The Journal of Organic Chemistry. 66 (25): 8447–53. doi:10.1021/jo015854w. PMID 11735524.
^Murphy JA, Tripoli R, Khan TA, Mali UW (July 2005). "Novel phosphorus radical-based routes to horsfiline". Organic Letters. 7 (15): 3287–9. doi:10.1021/ol051095i. PMID 16018642.
^Hong S, Jung M, Park Y, Ha MW, Park C, Lee M, Park HG (July 2013). "Efficient enantioselective total synthesis of (-)-horsfiline". Chemistry: A European Journal. 19 (29): 9599–605. doi:10.1002/chem.201301008. PMID 23836402.
^Mukaiyama T, Ogata K, Sato I, Hayashi Y (October 2014). "Asymmetric organocatalyzed Michael addition of nitromethane to a 2-oxoindoline-3-ylidene acetaldehyde and the three one-pot sequential synthesis of (-)-horsfiline and (-)-coerulescine". Chemistry: A European Journal. 20 (42): 13583–8. doi:10.1002/chem.201403932. PMID 25155110.
^Buev EM, Moshkin VS, Sosnovskikh VY (December 2017). "Nonstabilized Azomethine Ylides in the Mannich Reaction: Synthesis of 3,3-Disubstituted Pyrrolidines, Including Oxindole Alkaloids". The Journal of Organic Chemistry. 82 (23): 12827–12833. doi:10.1021/acs.joc.7b02193. PMID 29048900.
Horsfiline is an oxindole alkaloid found in the plant Horsfieldia superba, which is used in traditional herbal medicine. It has analgesic effects[medical...
coerulescens. It is a member of the spiroindolone class. Elacomine and horsfiline have similar chemical structures. Anderton, N., Cockrum, P. A., Colegate...
another ring in a spiro arrangement. Alkaloids in this class include horsfiline, rhynchophylline, gelsemine, carapanaubine, and maremycin E. Spiroindolones...
is used in traditional herbal medicine and contains an alkaloid called horsfiline, which has analgesic effects, as well as several other compounds including...
for timber. Species in the genus sometimes contain alkaloids, including horsfiline, which has analgesic effects. Plants of the World Online currently (February...
232.27 g/mol, exact mass : 232.121178) may refer to: Aminoglutethimide Horsfiline 4,5-MDO-DMT 5,6-MDO-DMT Melatonin, a hormone Methylphenylpiracetam Mofebutazone...