Histophilus somni is a non-motile, gram-negative, rod or coccobacillus shaped, facultative anaerobe bacterial species belonging to the family Pasteurellaceae.[2] Prior to 2003, it was thought Haemophilus somnus, Histophilus ovis, and Histophilus agni were three different species, but now are all classified as Histophilus somni. Histophilus somni is a commensal bacteria of mucous membranes of the upper respiratory tract and reproductive tract[3][4][5][6] with a global prevalence[6] and is found in cattle and other small ruminants.[4]Histophilus somni is also a known causative agent that is a part of the Bovine Respiratory Disease (BRD) complex,[4] which typically involves multiple pathogens residing together in biofilm environments. Histophilus somni may also cause Histophilosus symptoms and clinical presentation will depend on the tissue affected.[5] When disease does occur, it can be difficult to catch in time and is often diagnosed on post mortem.[7] This means that treatment often involves metaphylactic mass treatment or no treatment at all. This organism is more fastidious than others and requires knowledge for sample collection, storage and culture. Genomic studies related to this bacteria have enabled scientist to pin point antibiotic resistance genes.
^Markey, Bryan; Leonard, Finola; Archambault, Marie; Cullinane, Ann; Maguire, Dores (2013). "Chapter 26. Haemophilus and Histophilus species". Clinical Veterinary Microbiology (2nd ed.). Elsevier. p. 349. ISBN 9780702055881.
^Markey, Bryan K. (2013). Clinical veterinary microbiology. Elsevier. ISBN 9780702055881. OCLC 818985683.
^Grissett, G.P.; White, B.J.; Larson, R.L. (2015). "Structured Literature Review of Responses of Cattle to Viral and Bacterial Pathogens Causing Bovine Respiratory Disease Complex". Journal of Veterinary Internal Medicine. 29 (3): 770–780. doi:10.1111/jvim.12597. PMC 4895424. PMID 25929158.
^ abcBaptiste, Keith Edward; Kyvsgaard, Niels Christian (2017-09-29). "Do antimicrobial mass medications work? A systematic review and meta-analysis of randomised clinical trials investigating antimicrobial prophylaxis or metaphylaxis against naturally occurring bovine respiratory disease". Pathogens and Disease. 75 (7). doi:10.1093/femspd/ftx083. ISSN 2049-632X. PMC 7108556. PMID 28830074.
^ abSandal, Indra; Inzana, Thomas J. (2010-02-01). "A genomic window into the virulence of Histophilus somni". Trends in Microbiology. 18 (2): 90–99. doi:10.1016/j.tim.2009.11.006. ISSN 0966-842X. PMID 20036125.
^O’Toole, D.; Sondgeroth, K. S. (2015), Inzana, Thomas J. (ed.), "Histophilosis as a Natural Disease", Histophilus somni, vol. 396, Cham: Springer International Publishing, pp. 15–48, doi:10.1007/82_2015_5008, ISBN 978-3-319-29554-1, PMC 7120429, PMID 26847357
somnus, Histophilus ovis, and Histophilus agni were three different species, but now are all classified as Histophilussomni. Histophilussomni is a commensal...
associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilussomni, for treatment of bovine interdigital phlegmon (foot rot, acute interdigital...
associated with Mannheimia haemolytica, Pasteurella multocida, and Histophilussomni in beef and non-lactating dairy cattle. In the European Union, tildipirosin...
expressed in different tissues. Second, some common cattle pathogens like Histophilussomni and Mannheimia haemolytica have significantly different sensitivity...
(BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilussomni, and Mycoplasma bovis sensitive to tulathromycin. Treatment of infectious...
linked with BRD are Mannheimia haemolytica, Pasteurella multocida, Histophilussomni, and Mycoplasma bovis. M. haemolytica serovar A1 is known as a particularly...
(BRD) associated with Mannheimia haemolytica, Pasteurella multocida, Histophilussomni, and Mycoplasma bovis. It may only be prescribed for cattle intended...