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Hexaminolevulinate information


Hexaminolevulinate
Clinical data
Trade namesCysview, Hexvix
License data
  • US DailyMed: Hexaminolevulinate
ATC code
  • V04CX06 (WHO)
Legal status
Legal status
  • AU: S4 (Prescription only)[1]
  • CA: ℞-only
  • US: ℞-only[2]
Identifiers
CAS Number
  • 140898-97-1
PubChem CID
  • 6433083
DrugBank
  • DB06261
ChemSpider
  • 4938272
UNII
  • G7H20TKI67
KEGG
  • D04436
ChEBI
  • CHEBI:134892
ChEMBL
  • ChEMBL1201784
CompTox Dashboard (EPA)
  • DTXSID40161487 Edit this at Wikidata

Hexaminolevulinate, sold under the brand name Cysview among others, is an imaging agent that lights up under blue light during a blue light cystoscopy. It is used to help detect non-muscle invasive bladder cancer (NMIBC), in particular papillary tumors and carcinoma in situ (CIS).

It made by Photocure ASA, a Norwegian pharmaceutical company.

Hexaminolevulinate is a structural analogue to 5-aminolevulinic acid (a precursor to the porphyrin ring of heme), and is internalized and processed into the photoactive protoporphyrin IX at a high rate by tumor cells. After exposure to 360-450 nm light, the porphyrin will fluoresce red.[1]

  1. ^ "Prescription medicines: registration of new chemical entities in Australia, 2016". Therapeutic Goods Administration (TGA). 21 June 2022. Retrieved 10 April 2023.
  2. ^ "Cysview- hexaminolevulinate hydrochloride kit". DailyMed. 15 November 2022. Retrieved 10 April 2023.

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Hexaminolevulinate

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Hexaminolevulinate, sold under the brand name Cysview among others, is an imaging agent that lights up under blue light during a blue light cystoscopy...

Word Count : 139

ATC code V04

Last Update:

acid V04CX03 Methacholine V04CX04 Mannitol V04CX05 13C-urea V04CX06 Hexaminolevulinate V04CX07 Edrophonium V04CX08 Carbon monoxide V04CX09 Patent blue V04CX10...

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Bladder cancer

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treatment. Additionally, blue light cystoscopy with optical-imaging agent Hexaminolevulinate (HAL) is recommended at initial TURBT to increase lesion detection...

Word Count : 13535

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