Global InformationHexahydrocannabivarin information
 | |
| Identifiers | |
|---|---|
IUPAC name
| |
| Chemical and physical data | |
| Formula | C19H28O2 |
| Molar mass | 288.431 g·mol−1 |
| 3D model (JSmol) |
|
SMILES
| |
Hexahydrocannabivarin (HHCV, HHC-V) is a semi-synthetic cannabinoid derivative, the hydrogenated derivative of tetrahydrocannabivarin (THCV). It was first synthesised by Roger Adams in 1942 and produces only weak cannabinoid-like effects in animals.[1] More recently it has been sold as an ingredient in grey-market cannabinoid products. It has been investigated for potential antineoplastic activity in vitro.[2][3]
- ^ Adams R, Loewe S, Smith CM, McPhee WD (March 1942). "Tetrahydrocannabinol homologs and analogs with marihuana activity. XIII". Journal of the American Chemical Society. 64 (3): 694–697. doi:10.1021/ja01255a061.
- ^ Tesfatsion T, Collins A, Ramirez G, Mzannar Y, Khan H, Aboukameel O, Azmi A, Jagtap P, Ray K, Cruces W (2022). "Antineoplastic Properties of THCV, HHC, HHCV and their anti-Proliferative effects on HPAF-II, MIA-paca2, Aspc-1, and PANC-1 PDAC Pancreatic Cell Lines". ChemRxiv. doi:10.26434/chemrxiv-2022-v4zqc.
- ^ Docampo-Palacios ML, Ramirez GA, Tesfatsion TT, Okhovat A, Pittiglio M, Ray KP, Cruces W (September 2023). "Saturated Cannabinoids: Update on Synthesis Strategies and Biological Studies of These Emerging Cannabinoid Analogs". Molecules (Basel, Switzerland). 28 (17): 6434. doi:10.3390/molecules28176434. PMC 10490552. PMID 37687263.